Recombinant人TIE1 protein (Fc Chimera) (ab73870)

概述

描述

  • 性质
    Recombinant
  • 来源
    Baculovirus
  • 氨基酸序列
    • 种属
      Human
    • 额外的序列信息
      Fused with the Fc part of human IgG1.

技术指标

Our Abpromise guarantee covers the use of ab73870 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 90 % SDS-PAGE.
    ab73870 is purified by proprietary chromatographic techniques. Purity is greater than 90.0% as determined by RP-HPLC and SDS-PAGE.
  • 形式
    Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Sucrose, 0.5M Sodium chloride, 20mM Tris

  • 复溶
    Reconstitute in sterile water not less than 100µg/ml, which can then be further diluted to other aqueous solutions. Upon reconstitution ab73870 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.

常规信息

  • 别名
    • JKT 14
    • JTK14
    • TIE
    • Tie1
    • TIE1_HUMAN
    • Tyrosine Kinase with Immunoglobulin and Epidermal Growth Factor Homology Domains
    • Tyrosine kinase with immunoglobulin and epidermal growth factor homology domains 1
    • Tyrosine kinase with immunoglobulin-like and EGF-like domains 1
    • Tyrosine protein kinase receptor Tie 1
    • Tyrosine-protein kinase receptor Tie-1
    see all
  • 功能
    Transmembrane tyrosine-protein kinase that may modulate TEK/TIE2 activity and contribute to the regulation of angiogenesis.
  • 组织特异性
    Specifically expressed in developing vascular endothelial cells.
  • 序列相似性
    Belongs to the protein kinase superfamily. Tyr protein kinase family. Tie subfamily.
    Contains 3 EGF-like domains.
    Contains 3 fibronectin type-III domains.
    Contains 2 Ig-like C2-type (immunoglobulin-like) domains.
    Contains 1 protein kinase domain.
  • 翻译后修饰
    Phosphorylated on tyrosine residues in response to ANGPT1, most likely by TEK/TIE2.
  • 细胞定位
    Cell membrane.
  • Information by UniProt

文献

ab73870 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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