Recombinant人Thyroid Hormone Receptor alpha 1 protein (ab81885)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 额外的序列信息This protein is GST-tagged.

技术指标

Our Abpromise guarantee covers the use of ab81885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Functional Studies

  • 纯度> 95 % SDS-PAGE.
    ab81885 is purified by a combination of affinity and gel filtration chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

常规信息

  • 别名
    • c-erbA-1
    • C-erbA-alpha
    • EAR-7
    • ERBA
    • Nuclear receptor subfamily 1 group A member 1
    • THA_HUMAN
    • THRA
    • Thra1
    • Thyroid hormone receptor alpha
    • Thyroid hormone receptor alpha 1
    • TR alpha 1
    • V-erbA-related protein 7
    see all
  • 功能Nuclear hormone receptor. High affinity receptor for triiodothyronine.
  • 疾病相关Hypothyroidism, congenital, non-goitrous, 6 (CHNG6) [MIM:614450]: A disease characterized by growth retardation, developmental retardation, skeletal dysplasia, borderline low thyroxine levels and high triiodothyronine levels. There is differential sensitivity to thyroid hormone action, with retention of hormone responsiveness in the hypothalamic pituitary axis and liver but skeletal, gastrointestinal, and myocardial resistance. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 序列相似性Belongs to the nuclear hormone receptor family. NR1 subfamily.
    Contains 1 nuclear receptor DNA-binding domain.
  • 结构域Composed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human Thyroid Hormone Receptor alpha 1 protein (ab81885)参考文献

ab81885 has not yet been referenced specifically in any publications.

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