Recombinant人Thymidine Phosphorylase protein (ab101169)

概述

  • 产品名称Recombinant人Thymidine Phosphorylase protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP19971
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMAPPAPGDFSGEGSQGLPDPSPEPKQLPEL IRMKRDGGRLSEADIRGFVAAVVNGSAQGAQIGAMLMAIRLRGMDLEETS VLTQALAQSGQQLEWPEAWRQQLVDKHSTGGVGDKVSLVLAPALAACGCK VPMISGRGLGHTGGTLDKLESIPGFNVIQSPEQMQVLLDQAGCCIVGQSE QLVPADGILYAARDVTATVDSLPLITASILSKKLVEGLSALVVDVKFGGA AVFPNQEQARELAKTLVGVGASLGLRVAAALTAMDKPLGRCVGHALEVEE ALLCMDGAGPPDLRDLVTTLGGALLWLSGHAGTQAQGAARVAAALDDGSA LGRFERMLAAQGVDPGLARALCSGSPAERRQLLPRAREQEELLAPADGTV ELVRALPLALVLHELGAGRSRAGEPLRLGVGAELLVDVGQRLRRGTPWLR VHRDGPALSGPQSRALQEALVLSDRAPFAAPSPFAELVLPPQQ
    • 分子量51 kDa including tags
    • 氨基酸11 to 482
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101169 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab101169 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • ECGF
    • ECGF 1
    • ECGF1
    • Endothelial cell growth factor 1
    • Endothelial cell growth factor 1 platelet derived
    • Endothelial cell growth factor, platelet-derived
    • Gliostatin
    • hPD ECGF
    • MEDPS1
    • MNGIE
    • MTDPS1
    • PD ECGF
    • PD-ECGF
    • PDECGF
    • PDEGF
    • Platelet derived endothelial cell growth factor
    • Platelet derived endothelial growth factor
    • Platelet-derived endothelial cell growth factor
    • TdRPase
    • Thymidine phosphorylase
    • TP
    • Tymp
    • TYPH_HUMAN
    see all
  • 功能May have a role in maintaining the integrity of the blood vessels. Has growth promoting activity on endothelial cells, angiogenic activity in vivo and chemotactic activity on endothelial cells in vitro.
    Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.
  • 通路Pyrimidine metabolism; dTMP biosynthesis via salvage pathway; dTMP from thymine: step 1/2.
  • 疾病相关Mitochondrial DNA depletion syndrome 1 (MTDPS1) [MIM:603041]: A multisystem disease associated with mitochondrial dysfunction. It is clinically characterized by onset between the second and fifth decades of life, ptosis, progressive external ophthalmoplegia, gastrointestinal dysmotility (often pseudoobstruction), diffuse leukoencephalopathy, cachexia, peripheral neuropathy, and myopathy. Note=The disease is caused by mutations affecting the gene represented in this entry.
  • 序列相似性Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
  • Information by UniProt

Recombinant Human Thymidine Phosphorylase protein 图像

  • 15% SDS-PAGE showing ab101169 at approximately 51.3kDa (3µg).

Recombinant Human Thymidine Phosphorylase protein (ab101169)参考文献

ab101169 has not yet been referenced specifically in any publications.

Product Wall



The endotoxins have not been removed, but the lab has tested the protein and the endotoxin level is low, ie. 0.37 EU/ug (determined by LAL method).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"