Recombinant人TGF beta 3 protein (ab52313)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列ALDTNYCFRN LEENCCVRPL YIDFRQDLGW KWVHEPKGYY ANFCSGPCPY LRSADTTHST VLGLYNTLNP EASASPCCVP QDLEPLTILY YVGRTPKVEQ LSNMVVKSCK CS
    • 分子量25 kDa
    • 氨基酸301 to 412

技术指标

Our Abpromise guarantee covers the use of ab52313 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性TGF beta 3 is fully biologically active when compared to standard. The ED50 determined by cytotoxicity assay using the world health organization standard 98/608 as a direct comparison is <0.05 ng/ml, corresponding to a specific activity of >2 x 108 units/mg.
  • 应用

    Western blot

    Functional Studies

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    >99% by SDS-PAGE and HPLC analyses
  • 形式Liquid
  • 补充说明This protein solution should be stored at 4°C, stable for at least 3 months. For long term storage, it is recommended to add a carrier protein (0.1% HAS or BSA).
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C.

    Preservative: None
    Constituents: 20% Ethanol and 0.1% Acetate.
    Endotoxin level is <0.1 ng per µg.

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

常规信息

  • 别名
    • ARVD
    • ARVD1
    • FLJ16571
    • MGC105479
    • MGC118722
    • prepro-transforming growth factor beta-3
    • RNHF
    • TGF beta 3
    • TGF beta3
    • TGF-beta-3
    • TGFB 3
    • Tgfb3
    • TGFB3_HUMAN
    • transforming growth factor beta 3
    • Transforming growth factor beta-3
    see all
  • 功能Involved in embryogenesis and cell differentiation.
  • 疾病相关Defects in TGFB3 are a cause of familial arrhythmogenic right ventricular dysplasia type 1 (ARVD1) [MIM:107970]; also known as arrhythmogenic right ventricular cardiomyopathy 1 (ARVC1). ARVD is an autosomal dominant disease characterized by partial degeneration of the myocardium of the right ventricle, electrical instability, and sudden death. It is clinically defined by electrocardiographic and angiographic criteria; pathologic findings, replacement of ventricular myocardium with fatty and fibrous elements, preferentially involve the right ventricular free wall.
  • 序列相似性Belongs to the TGF-beta family.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human TGF beta 3 protein 图像

  • Anti-TGF beta 3 antibody (ab15537) at 1/200 dilution + Recombinant human TGF beta 3 protein (ab52313) at 0.01 µg

    Secondary
    Goat Anti-Rabbit IgG H&L (HRP) preadsorbed (ab97080) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 30 seconds

Recombinant human TGF beta 3 protein (ab52313)参考文献

ab52313 has not yet been referenced specifically in any publications.

Product Wall

The composition of the storage buffer of the ab52313 is 20% Ethanol and 0.1% Acetate.
Since there is 20% ethanol in the solution, hopefully the protein might not be fully frozen at -20C. Therefore, there is a possibility that the protein still wor...

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"