Recombinant人TFB1M protein (ab113141)

概述

  • 产品名称Recombinant人TFB1M protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ8WVM0
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMQAAKQLSQNFLLDLRLTDKIVRKAGNLTN AYVYEVGPGPGGITRSIL NADVAELLVVEKDTRFIPGLQMLSDAAPGK LRIVHGDVLTFKVEKAFSESLKRPWEDDPPNVHIIGNLPFSVSTP LII KWLENISCRDGPFVYGRTQMTLTFQKEVAERLAANTGSKQRSRLSVMAQY LCNVRHIFTIPGQAFVPKPEVD VGVVHFTPLIQPKIEQPFKLVEKVVQ NVFQFRRKYCHRGLRMLFPEAQRLESTGRLLELADIDPTLRPRQLSISH FKSLCDVYRKMCDEDPQLFAYNFREELKRRKSKNEEKEEDDAENYRL
    • 分子量39 kDa including tags
    • 氨基酸28 to 346
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab113141 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Functional Studies

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab113141 was purified using conventional chromatography.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • CGI75
    • Dimethyladenosine transferase 1, mitochondrial
    • h-mtTFB
    • h-mtTFB1
    • hmtTFB
    • hmtTFB1
    • hTFB1M
    • Mitochondrial 12S rRNA dimethylase 1
    • Mitochondrial dimethyladenosine transferase 1
    • Mitochondrial transcription factor B1
    • mtTFB1
    • N'-adenosyl(rRNA) dimethyltransferase 1
    • S-adenosylmethionine-6-N'
    • Tfb1m
    • TFB1M_HUMAN
    • Transcription factor B1 mitochondrial
    see all
  • 功能S-adenosyl-L-methionine-dependent methyltransferase which specifically dimethylates mitochondrial 12S rRNA at the conserved stem loop. Also required for basal transcription of mitochondrial DNA, probably via its interaction with POLRMT and TFAM. Stimulates transcription independently of the methyltransferase activity.
  • 组织特异性Ubiquitously expressed.
  • 疾病相关Note=Variations in TFB1M may influence the clinical expression of aminoglycoside-induced deafness caused by the A1555G mutation in the mitochondrial 12S rRNA.
  • 序列相似性Belongs to the methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. KsgA subfamily.
  • 细胞定位Mitochondrion.
  • Information by UniProt

Recombinant Human TFB1M protein 图像

  • 15% SDS-PAGE analysis of ab113141 (3µg)

Recombinant Human TFB1M protein (ab113141)参考文献

ab113141 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab113141.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"