来源 Escherichia coli
序列 MGSSHHHHHHSSGLVPRGSHMDLENKVKKMGLGHEQGFGAPCLKCKEKCE GFELHFWRKICRNCKCGQEEHDVLLSNEEDRKVGKLFEDTKYTTLIAKLK SDGIPMYKRNVMILTNPVAAKKNVSINTVTYEWAPPVQNQALARQYMQML PKEKQPVAGSEGAQYRKKQLAKQLPAHDQDPSKCHELSPREVKEMEQFVK KYKSEALGVGDVKLPCEMDAQGPKQMNIPGGDRSTPAAVGAMEDKSAEHK RTQYSCYCCKLSMKEGDPAIYAERAGYDKLWHPACFVCSTCHELLVDMIY FWKNEKLYCGRHYCDSEKPRCAGCDELIFSNEYTQAENQNWHLKHFCCFD CDSILAGEIYVMVNDKPVCKPCYVKNHAVVCQGCHNAIDPEVQRVTYNNF SWHASTECFLCSCCSKCLIGQKFMPVEGMVFCSVECKKRMS
分子量 50 kDa including tags
氨基酸 1 to 421
标签 His tag N-Terminus 技术指标
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
纯度 > 90
% SDS-PAGE. ab99213 was purified using conventional chromatography techniques.
Concentration information loading... 制备和贮存
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
功能 Scaffold protein that may play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton. Plays a role in the regulation of cell proliferation. May act as a tumor suppressor. Inhibits tumor cell growth.
序列相似性 Belongs to the prickle / espinas / testin family. Contains 3 LIM zinc-binding domains. Contains 1 PET domain.
结构域 The N-terminal and the C-terminal halves of the protein can associate with each other, thereby hindering interactions with ZYX.
细胞定位 Cytoplasm. Cell junction > focal adhesion. Detected along actin stress fibers.
Information by UniProt
Recombinant Human Testin protein 图像
Recombinant Human Testin protein (ab99213)参考文献
has not yet been referenced specifically in any publications.
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