Recombinant人Tcl1 protein (ab87690)

概述

  • 产品名称
    Recombinant人Tcl1 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MAECPTLGEA VTDHPDRLWA WEKFVYLDEK QHAWLPLTIE IKDRLQLRVL LRREDVVLGR PMTPTQIGPS LLPIMWQLYP DGRYRSSDSS FWRLVYHIKI DGVEDMLLEL LPDD

技术指标

Our Abpromise guarantee covers the use of ab87690 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 90 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 50mM Tris HCl, pH 7.5

常规信息

  • 别名
    • Anti TCL1A
    • Lymphoma/leukemia, T-cell
    • Oncogene TCL-1
    • Oncogene TCL1
    • P14 TCL1
    • P14 TCL1 protein
    • Protein p14 TCL1
    • T cell leukemia 1
    • T cell lymphoma 1
    • T cell lymphoma 1A
    • T-cell leukemia/lymphoma 1A
    • T-cell leukemia/lymphoma protein 1A
    • TCL 1 protein
    • TCL1
    • TCL1 oncogene
    • TCL1 PEN
    • Tcl1a
    • TCL1A antibody
    • TCL1A_HUMAN
    see all
  • 功能
    Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes mitochondrial membrane potential and promotes cell survival.
  • 组织特异性
    Restricted in the T-cell lineage to immature thymocytes and activated peripheral lymphocytes. Preferentially expressed early in T- and B-lymphocyte differentiation.
  • 疾病相关
    Note=Chromosomal aberrations activating TCL1A are found in chronic T-cell leukemias (T-CLL). Translocation t(14;14)(q11;q32); translocation t(7;14)(q35;q32); inversion inv(14)(q11;q32) that involves the T-cell receptor alpha/delta loci.
  • 序列相似性
    Belongs to the TCL1 family.
  • 细胞定位
    Cytoplasm. Nucleus. Microsome. Endoplasmic reticulum. Microsomal fraction.
  • Information by UniProt

Recombinant Human Tcl1 protein 图像

  • ab87690 on 15% SDS-PAGE (3µg)

Recombinant Human Tcl1 protein (ab87690)参考文献

ab87690 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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