Recombinant人TCEAL1 protein (ab108377)

概述

  • 产品名称
    Recombinant人TCEAL1 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MDKPRKENEEEPQSAPKTDEERPPVEHSPEKQSPEEQSSEEQSSEEEFFP EELLPELLPEMLLSEERPPQEGLSRKDLFEGRPPMEQPPCGVGKHKLEEG SFKERLARSRPQFRGDIHGRNLSNEEMIQAADELEEMKRVRNKLMIMHWK AKRSRPYPILEHHHHHH
    • 分子量
      20 kDa including tags
    • 氨基酸
      1 to 159
    • 标签
      His tag C-Terminus

技术指标

Our Abpromise guarantee covers the use of ab108377 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab108377 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 2mM DTT, pH 8.0

常规信息

  • 别名
    • Highly similar to gene pp21 protein [H.sapiens]
    • Nuclear phosphoprotein p21/SIIR
    • p21
    • pp21
    • SIIR
    • TCAL1_HUMAN
    • TCEA like protein 1
    • TCEA-like protein 1
    • TCEAL1
    • Transcription elongation factor A (SII) like 1
    • Transcription elongation factor A protein like 1
    • Transcription elongation factor A protein-like 1
    • Transcription elongation factor S II protein like 1
    • Transcription elongation factor S-II protein-like 1
    see all
  • 功能
    May be involved in transcriptional regulation. Modulates various viral and cellular promoters in a promoter context-dependent manner. For example, transcription from the FOS promoter is increased, while Rous sarcoma virus (RSV) long terminal repeat (LTR) promoter activity is repressed. Does not bind DNA directly.
  • 组织特异性
    Expressed in all tissues examined. Highly expressed in heart, ovary, prostate and skeletal muscle. Moderately expressed in brain, placenta, testis and small intestine. Weakly expressed in lung, liver and spleen. Expressed in several cancer cell lines.
  • 序列相似性
    Belongs to the TFS-II family. TFA subfamily.
  • 翻译后修饰
    Phosphorylation of Ser-36 and Ser-37 is critical for transcriptional repression.
  • 细胞定位
    Nucleus.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of ab108377 (3µg)

文献

ab108377 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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