Recombinant人Tau410 protein (ab72462)

概述

  • 产品名称Recombinant人Tau410 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP10636-5
    • 种属Human
    • 序列MAEPRQEFEVMEDHAGTYGLGDRKDQGGYTMHQDQEGDTDAGLKESPLQT PTEDGSEEPGSETSDAKSTPTAEDVTAPLVDEGAPGKQAAAQPHTEIPEG TTAEEAGIGDTPSLEDEAAGHVTQARMVSKSKDGTGSDDKKAKGADGKTK IATPRGAAPPGQKGQANATRIPAKTPPAPKTPPSSGEPPKSGDRSGYSSP GSPGTPGSRSRTPSLPTPPTREPKKVAVVRTPPKSPSSAK SRLQTAPV PMPDLKNVKSKIGSTENLKHQPGGGKVQIVYKPVDLSKVTSKCGSLGNIH HKPGGGQVEVKSEKLDFKDRVQSKIGSLDNITHVPGGGNKKIETHKLTFR ENAKAKTDHGAEIVYKSPVVSGDTSPRHLSNVSSTGSIDMVDSPQLATLA DEVSASLAKQGL
    • 氨基酸1 to 410
    • 额外的序列信息This is full length isoform P10636-5, Tau-C.

技术指标

Our Abpromise guarantee covers the use of ab72462 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 形式Liquid
  • 补充说明

    This protein is full-length isoform 5, Isoform Tau-C.

  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • DDPAC
    • FLJ31424
    • FTDP 17
    • FTDP17
    • G protein beta1/gamma2 subunit interacting factor 1
    • MAPT
    • MAPTL
    • MGC138549
    • Microtubuleassociated protein tau
    • MSTD
    • MTBT1
    • MTBT2
    • Neurofibrillary tangle protein
    • Paired helical filament tau
    • PHF tau
    • PPND
    • TAU
    see all
  • 相关性Tau410 or Tau C is a member of the Tau family of proteins. Tau proteins promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. The C-terminus binds axonal microtubules while the N-terminus binds neural plasma membrane components, suggesting that tau functions as a linker protein between both. Axonal polarity is predetermined by tau localization (in the neuronal cell) in the domain of the cell body defined by the centrosome. The short isoforms allow plasticity of the cytoskeleton whereas the longer isoforms may preferentially play a role in its stabilization.
  • 细胞定位Cytoplasm, cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, axon. Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components.

Recombinant Human Tau410 protein 图像

  • SDS-PAGE showing ab72462 at approximately 61kDa.

Recombinant Human Tau410 protein (ab72462)参考文献

ab72462 has not yet been referenced specifically in any publications.

Product Wall

Ab72461: Tau D (383 amino acids long) Ab72462: Tau C (410 amino acids long) Ab72463: Tau E (412 amino acids long) Ab72489: Tau F, only amino acids 1-391

The isoform of ab72462 is the 410 kDa tau protein, also known as Tau-C according to uniProt:
http://www.uniprot.org/uniprot/P10636

Thank you for contacting us.

The link to the UniProt database entry is as follows:
http://pir.uniprot.org/uniprot/P10636

ab72462: P10636-5 corresponds to Tau-3

ab72489: P10636-8 corresponds to Tau-4


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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"