Recombinant人Tau383 protein (ab84766)

概述

  • 产品名称
    Recombinant人Tau383 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 氨基酸
      1 to 383

相关产品

技术指标

Our Abpromise guarantee covers the use of ab84766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 25% Glycerol, 50mM Tris HCl, 150mM Sodium chloride, 0.25mM DTT, 0.1mM PMSF, pH 7.5

常规信息

  • 别名
    • AI413597
    • AW045860
    • DDPAC
    • FLJ31424
    • FTDP 17
    • G protein beta1/gamma2 subunit-interacting factor 1
    • MAPTL
    • MGC138549
    • MGC156663
    • Microtubule associated protein tau
    • Microtubule associated protein tau, isoform 4
    • MSTD
    • Mtapt
    • MTBT1
    • MTBT2
    • Neurofibrillary tangle protein
    • OTTMUSP00000003078
    • OTTMUSP00000003083
    • Paired helical filament-tau
    • PHF tau
    • PPND
    • pTau
    • rCG_32645
    • RNPTAU
    • RP23-136D4.1
    • TAU
    • Tau D
    see all
  • 相关性
    Tau383 is a memeber of the family of neuronal microtubule-associated proteins. Tau promotes assembly and stabilizes neuronal microtubules under normal physiological conditions, but under pathological conditions can also undergo modifications such as hyperphosphorylation, that can result in the generation of aberrant aggregates such as found in neurofibrillary tangles in Alzheimer's disease. Six isoforms have been found that differ from each other in having either 3 or 4 binding repeats (R) of 31-32 amino acids, and from zero to 3 amino terminal inserts (N) of 29 amino acids each.
  • 细胞定位
    Cytoplasm; cytosol. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm; cytoskeleton. Cell projection; axon. Note: Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components

图片

  • SDS-PAGE showing ab84766 at approximately 52kDa.

文献

ab84766 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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