Recombinant人Syntenin protein (ab101950)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMSLYPSLEDLKVDKVIQAQTAFSANPANPA ILSEASAPIPHDGNLYPRLYPELSQYMGLSLNEEEIRANVAVVSGAPLQG QLVARPSSINYMVAPVTGNDVGIRRAEIKQGIREVILCKDQDGKIGLRLK SIDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQ AFGEKITMTIRDRPFERTITMHKDSTGHVGFIFKNGKITSIVKDSSAARN GLLTEHNICEINGQNVIGLKDSQIADILSTSGTVVTITIMPAFIFEHIIK RMAPSIMKSLMDHTIPEV
    • 分子量
      35 kDa including tags
    • 氨基酸
      1 to 298
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101950 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    ab101950 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 40% Glycerol, 20mM Tris HCl, 100mM Sodium chloride, pH 8.0

常规信息

  • 别名
    • MDA-9
    • MDA9
    • Melanoma differentiation-associated protein 9
    • Pro-TGF-alpha cytoplasmic domain-interacting protein 18
    • Scaffold protein Pbp1
    • SDCB1_HUMAN
    • SDCBP
    • ST1
    • SYCL
    • Syndecan binding protein (syntenin)
    • Syndecan binding protein 1
    • Syndecan-binding protein 1
    • Syntenin 1
    • Syntenin-1
    • TACIP18
    see all
  • 功能
    Seems to function as an adapter protein. In adherens junctions may function to couple syndecans to cytoskeletal proteins or signaling components. Seems to couple transcription factor SOX4 to the IL-5 receptor (IL5RA). May also play a role in vesicular trafficking. Seems to be required for the targeting of TGFA to the cell surface in the early secretory pathway.
  • 组织特异性
    Widely expressed. Expressed in fetal kidney, liver, lung and brain. In adult highest expression in heart and placenta.
  • 序列相似性
    Contains 2 PDZ (DHR) domains.
  • 翻译后修饰
    Phosphorylated on tyrosine residues.
  • 细胞定位
    Cell junction > focal adhesion. Cell junction > adherens junction. Cell membrane. Endoplasmic reticulum membrane. Nucleus. Melanosome. Cytoplasm > cytosol. Cytoplasm > cytoskeleton. Mainly membrane-associated. Localized to adherens junctions, focal adhesions and endoplasmic reticulum. Colocalized with actin stress fibers. Also found in the nucleus. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
  • Information by UniProt

Recombinant Human Syntenin protein 图像

  • 15% SDS-PAGE analysis of 3µg ab101950.

Recombinant Human Syntenin protein (ab101950)参考文献

ab101950 has not yet been referenced specifically in any publications.

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