Recombinant人Syntaxin 1a protein (ab86442)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human
    • 序列MKDRTQELRT AKDSDDDDDV AVTVDRDRFM DEFFEQVEEI RGFIDKIAEN VEEVKRKHSA ILASPNPDEK TKEELEELMS DIKKTANKVR SKLKSIEQSI EQEEGLNRSS ADLRIRKTQH STLSRKFVEV MSEYNATQSD YRERCKGRIQ RQLEITGRTT TSEELEDMLE SGNPAIFASG IIMDSSISKQ ALSEIETRHS EIIKLENSIR ELHDMFMDMA MLVESQ
    • 氨基酸1 to 226

技术指标

Our Abpromise guarantee covers the use of ab86442 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.
    ab86442 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, 20mM Tris, 1mM DTT, pH 7.5

常规信息

  • 别名
    • HPC 1
    • Neuron specific antigen HPC1
    • Neuron-specific antigen HPC-1
    • OTTHUMP00000174615
    • OTTHUMP00000174616
    • OTTHUMP00000174617
    • OTTHUMP00000174618
    • P35-1
    • STX1
    • STX1A
    • STX1A_HUMAN
    • SYN1A
    • Syntaxin 1A (brain)
    • Syntaxin 1A brain
    • Syntaxin-1A
    see all
  • 功能Potentially involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. May mediate Ca(2+)-regulation of exocytosis acrosomal reaction in sperm.
  • 组织特异性Isoform 1 is highly expressed in embryonic spinal chord and ganglia and in adult cerebellum and cerebral cortex. Isoform 2 is expressed in heart, liver, fat, skeletal muscle, kidney and brain.
  • 疾病相关Note=STX1A is located in the Williams-Beuren syndrome (WBS) critical region. WBS results from a hemizygous deletion of several genes on chromosome 7q11.23, thought to arise as a consequence of unequal crossing over between highly homologous low-copy repeat sequences flanking the deleted region.
  • 序列相似性Belongs to the syntaxin family.
    Contains 1 t-SNARE coiled-coil homology domain.
  • 细胞定位Secreted and Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome.
  • Information by UniProt

Recombinant Human Syntaxin 1a protein 图像

  • 15% SDS-PAGE showing ab86442 at approximately 26.1kDa.

Recombinant Human Syntaxin 1a protein (ab86442)参考文献

ab86442 has not yet been referenced specifically in any publications.

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