重组人Surfactant蛋白D/SP-D (denatured) (ab181961)
Key features and details
- Expression system: Escherichia coli
- Purity: > 85% SDS-PAGE
- Tags: His tag N-Terminus
- Suitable for: SDS-PAGE
描述
-
产品名称
重组人Surfactant蛋白D/SP-D (denatured)
参阅全部 Surfactant protein D/SP-D 蛋白酶 -
纯度
> 85 % SDS-PAGE. -
表达系统
Escherichia coli -
Accession
-
蛋白长度
Protein fragment -
无动物成分
No -
性质
Recombinant -
-
种属
Human -
序列
VASLRQQ VEALQGQVQH LQAAFSQYKK VELFPNGQSV GEKIFKTAGF VKPFTEAQLL CTQAGGQLAS PRSAAENAAL QQLVVAKNEA AFLSMTDSKT EGKFTYPTGE SLVYSNWAPG EPNDDGGSED CVEIFTNGKW NDRACGEKRL VVCEF -
预测分子量
19 kDa including tags -
氨基酸
224 to 375 -
标签
His tag N-Terminus -
额外的序列信息
NP_003010
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab181961 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
-
形式
Liquid -
补充说明
Previously labelled as Surfactant protein D.
-
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
pH: 8.00
Constituents: 0.32% Tris HCl, 10% Glycerol (glycerin, glycerine), 2.4% Urea
常规信息
-
别名
- COLEC 7
- COLEC7
- Collectin-7
see all -
功能
Contributes to the lung's defense against inhaled microorganisms. May participate in the extracellular reorganization or turnover of pulmonary surfactant. Binds strongly maltose residues and to a lesser extent other alpha-glucosyl moieties. -
序列相似性
Belongs to the SFTPD family.
Contains 1 C-type lectin domain.
Contains 1 collagen-like domain. -
翻译后修饰
The N-terminus is blocked.
Hydroxylation on proline residues within the sequence motif, GXPG, is most likely to be 4-hydroxy as this fits the requirement for 4-hydroxylation in vertebrates. -
细胞定位
Secreted > extracellular space > extracellular matrix. Secreted > extracellular space > surface film. - Information by UniProt
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (1)
ab181961 被引用在 1 文献中.
- Wong SSW et al. Fungal melanin stimulates surfactant protein D-mediated opsonization of and host immune response to Aspergillus fumigatus spores. J Biol Chem 293:4901-4912 (2018). PubMed: 29414772