Recombinant人SUGT1 protein (ab103785)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9Y2Z0
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMHRVGQAGLQLLTSSDPPALDSQSAGITGA DANFSVWIKRCQEAQNGSESEVWTHQSKIKYDWYQTESQVVITLMIKNVQ KNDVNVEFSEKELSALVKLPSGEDYNLKLELLHPIIPEQSTFKVLSTKIE IKLKKPEAVRWEKLEGQGDVPTPKQFVADVKNLYPSSSPYTRNWDKLVGE IKEEEKNEKLEGDAALNRLFQQIYSDGSDEVKRAMNKSFMESGGTVLSTN WSDVGKRKVEINPPDDMEWKKY
    • 分子量31 kDa including tags
    • 氨基酸115 to 365
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103785 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab103785 was purified by using anion-exchange chromatography (DEAE sepharose resin) and gel-filtration chromatography (Sephacryl S-200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • Protein 40 6 3
    • Protein 40-6-3
    • Protein SGT1 homolog
    • Putative 40 6 3 protein
    • Sgt1
    • SGT1 suppressor of G2 allele of SKP1
    • SGT1_HUMAN
    • SGT1B protein
    • sugt1
    • Suppressor of G2 allele of SKP1 homolog
    • Suppressor of G2 allele of SKP1 S. cerevisiae homolog of
    see all
  • 功能May play a role in ubiquitination and subsequent proteasomal degradation of target proteins.
  • 序列相似性Belongs to the SGT1 family.
    Contains 1 CS domain.
    Contains 1 SGS domain.
    Contains 3 TPR repeats.
  • 结构域The CS domain mediates interaction with HSP90.
  • 翻译后修饰Phosphorylated at Ser-281 and Ser-331, dephosphorylation promotes nuclear translocation, most likely due to disruption of the SUGT1-HSP90 complex.
  • 细胞定位Cytoplasm. Nucleus. Translocates to the nucleus upon heat shock, requiring S100A6.
  • Information by UniProt

Recombinant Human SUGT1 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab103785.

Recombinant Human SUGT1 protein (ab103785)参考文献

ab103785 has not yet been referenced specifically in any publications.

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