Recombinant人SSX2 protein (ab116849)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ16385
    • 种属Human
    • 序列MNGDDAFARRPTVGAQIPEKIQKAFDDIAKYFSKEEWEKMKASEKIFYVY MKRKYEAMTKLGFKATLPPFMCNKRAEDFQGNDLDNDPNRGNQVERPQMT FGRLQGISPKIMPKKPAEEGNDSEEVPEASGPQNDGKELCPPGKPTTSEK IHERSGNREAQEKEERRGTAHRWSSQNTHNIGRFSLSTSMGAVHGTPKTI THNRDPKGGNMPGPTDCVRENSW
    • 分子量51 kDa including tags
    • 氨基酸1 to 223

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技术指标

Our Abpromise guarantee covers the use of ab116849 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Cancer/testis antigen 5.2
    • Cancer/testis antigen family 5, member 2a
    • Cancer/testis antigen family 5, member 2b
    • CT5.2
    • CT5.2A
    • CT5.2b
    • HD21
    • hom mel 40
    • HOM-MEL-40
    • MGC119055
    • MGC15364
    • MGC3884
    • Protein SSX2
    • RP11-552J9.2
    • sarcoma, synovial, X-chromosome related 2
    • SSx
    • SSX2
    • SSX2-SYT fusion gene, included
    • SSX2_HUMAN
    • SSX2B
    • Synovial sarcoma
    • synovial sarcoma X breakpoint 2
    • Synovial sarcoma, X breakpoint 2B
    • Tumor antigen HOM-MEL-40
    • X breakpoint 2
    see all
  • 功能Could act as a modulator of transcription.
  • 组织特异性Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
  • 疾病相关Note=A chromosomal aberration involving SSX2 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • 序列相似性Belongs to the SSX family.
    Contains 1 KRAB-related domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human SSX2 protein 图像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116849 at approximately 50.64 kDa.

Recombinant Human SSX2 protein (ab116849)参考文献

ab116849 has not yet been referenced specifically in any publications.

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