Recombinant人SS18 protein (ab116825)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ15532
    • 种属Human
    • 序列MSVAFAAPRQRGKGEITPAAIQKMLDDNNHLIQCIMDSQNKGKTSECSQY QQMLHTNLVYLATIADSNQNMQSLLPAPPTQNMPMGPGGMNQSGPPPPPR SHNMPSDGMVGGGPPAPHMQNQMNGQMPGPNHMPMQGPGPNQLNMTNSSM NMPSSSHGSMGGYNHSVPSSQSMPVQNQMTMSQGQPMGNYGPRPNMSMQP NQGPMMHQQPPSQQYNMPQGGGQHYQGQQPPMGMMGQVNQGNHMMGQRQI PPYRPPQQGPPQQYSGQEDYYGDQYSHGGQGPPEGMNQQYYPDGHNDYGY QQPSYPEQGYDRPYEDSSQHYYEGGNSQYGQQQDAYQGPPPQQGYPPQQQ QYPGQQGYPGQQQGYGPSQGGPGPQYPNYPQGQGQQYGGYRPTQPGPPQP PQQRPYGYDQGQYGNYQ
    • 分子量72 kDa including tags
    • 氨基酸1 to 418

技术指标

Our Abpromise guarantee covers the use of ab116825 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • MGC116875
    • Protein SSXT
    • Protein SYT
    • SS18
    • SSXT
    • SSXT/SSX4v fusion
    • SSXT_HUMAN
    • Synovial sarcoma translocated to X chromosome
    • Synovial sarcoma translocated to X chromosome protein
    • Synovial sarcoma translocation chromosome 18
    • SYT
    • SYT SSX1
    • SYT SSX2
    • SYT/SSX4v fusion protein
    • SYTSSX1
    • SYTSSX2
    see all
  • 功能Appears to function synergistically with RBM14 as a transcriptional coactivator. Isoform 1 and isoform 2 function in nuclear receptor coactivation. Isoform 1 and isoform 2 function in general transcriptional coactivation.
  • 组织特异性Fairly ubiquitously expressed. Expressed in synovial sarcomas and in other human cell lines. The fusion genes SSXT-SSX1 and SSXT-SSX2 are expressed only in synovial sarcomas.
  • 疾病相关Note=A chromosomal aberration involving SS18 may be a cause of synovial sarcoma. Translocation t(X;18)(p11.2;q11.2). The translocation is specifically found in more than 80% of synovial sarcoma. The fusion products SSXT-SSX1 or SSXT-SSX2 are probably responsible for transforming activity. Heterogeneity in the position of the breakpoint can occur (low frequency).
  • 序列相似性Belongs to the SS18 family.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human SS18 protein 图像

  • 12.5% SDS-PAGE stained with Coomassie Blue showing ab116825 at approximately 72.05 kDa.

Recombinant Human SS18 protein (ab116825)参考文献

ab116825 has not yet been referenced specifically in any publications.

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