Recombinant人SPOP protein (ab105599)

概述

  • 产品名称Recombinant人SPOP protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionO43791
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMSRVPSPPPPAEMSSGPVAESWCYTQIKVV KFSYMWTINNFSFCREEMGEVIKSSTFSSGANDKLKWCLRVNPKGLDEES KDYLSLYLLLVSCPKSEVRAKFKFSILNAKGEETKAMESQRAYRFVQGKD WGFKKFIRRDFLLDEANGLLPDDKLTLFCEVSVVQDSVNISGQNTMNMVK VPECRLADELGGLWENSRFTDCCLCVAGQEFQAHKAILAARSPVFSAMFE HEMEESKKNRVEINDVEPEVFKEMMCFIYTGKAPNLDKMADDLLAAADKY ALERLKVMCEDALCSNLSVENAAEILILADLHSADQLKTQAVDFINYHAS DVLETSGWKSMVVSHPHLVAEAYRSLASAQCPFLGPPRKRLKQS
    • 分子量44 kDa including tags
    • 氨基酸1 to 374
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab105599 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab105599 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 50% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, 2mM EDTA, pH 8.0

常规信息

  • 别名
    • BTBD32
    • HIB homolog 1
    • Roadkill homolog 1
    • Speckle type POZ protein
    • Speckle-type POZ protein
    • SPOP
    • SPOP_HUMAN
    • TEF 2
    • TEF2
    see all
  • 功能Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.
  • 组织特异性Widely expressed.
  • 通路Protein modification; protein ubiquitination.
  • 序列相似性Belongs to the Tdpoz family.
    Contains 1 BTB (POZ) domain.
    Contains 1 MATH domain.
  • 结构域The MATH domain interacts with H2AFY and BMI1.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human SPOP protein 图像

  • 15% SDS-PAGE analysis of 3µg ab105599.

Recombinant Human SPOP protein (ab105599)参考文献

ab105599 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"