概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MDPAGGPRGVLPRPCRVLVLLNPRGGKGKALQLFRSHVQPLLAEAEISFT LMLTERRNHARELVRSEELGRWDALVVMSGDGLMHEVVNGLMERPDWETA IQKPLCSLPAGSGNALAASLNHYAGYEQVTNEDLLTNCTLLLCRRLLSPM NLLSLHTASGLRLFSVLSLAWGFIADVDLESEKYRRLGEMRFTLGTFLLL AALRTYRGRLAYLPVGRVGSKTPASPVVVQQGPVDAHLVPLEEPVPSHWT VVPDEDFVLVLALLHSHLGSEMFAAPMGRCAAGVMHLFYVRAGVSRAMLL RLFLAMEKGRHMEYECPYLVYVPVVAFRLEPKDGKGVFAVDGELMVSEAV QGQVHPNYFWMVSGCVEPPPSWKPQQMPPPEEPL
    • 氨基酸
      1 to 384
    • 标签
      proprietary tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab152931 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • SK 1
    • SK1
    • Sphingosine kinase 1
    • SPHK
    • SPHK 1
    • Sphk1
    • SPHK1_HUMAN
    • SPK
    • SPK 1
    see all
  • 功能
    Catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra-and extracellular functions. Also acts on D-erythro-sphingosine and to a lesser extent sphinganine, but not other lipids, such as D,L-threo-dihydrosphingosine, N,N-dimethylsphingosine, diacylglycerol, ceramide, or phosphatidylinositol.
  • 组织特异性
    Widely expressed with highest levels in adult liver, kidney, heart and skeletal muscle.
  • 序列相似性
    Contains 1 DAGKc domain.
  • Information by UniProt

图片

  • ab152931 on a 12.5% SDS-PAGE stained with Coomassie Blue.

文献

ab152931 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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