Recombinant人Spermine synthase protein (ab116763)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MAAARHSTLDFMLGAKADGETILKGLQSIFQEQGMAESVHTWQDHGYLAT YTNKNGSFANLRIYPHGLVLLDLQSYDGDAQGKEEIDSILNKVEERMKEL SQDSTGRVKRLPPIVRGGAIDRYWPTADGRLVEYDIDEVVYDEDSPYQNI KILHSKQFGNILILSGDVNLAESDLAYTRAIMGSGKEDYTGKDVLILGGG DGGILCEIVKLKPKMVTMVEIDQMVIDGCKKYMRKTCGDVLDNLKGDCYQ VLIEDCIPVLKRYAKEGREFDYVINDLTAVPISTSPEEDSTWEFLRLILD LSMKVLKQDGKYFTQGNCVNLTEALSLYEEQLGRLYCPVEFSKEIVCVPS YLELWVFYTVWKKAKP
    • 分子量
      66 kDa including tags
    • 氨基酸
      1 to 366

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技术指标

Our Abpromise guarantee covers the use of ab116763 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • MRSR
    • SMS
    • Snyder Robinson X linked mental retardation syndrome
    • Spermidine aminopropyltransferase
    • Spermine synthase
    • SPMSY
    • SpS
    • SPSY_HUMAN
    • SRS
    see all
  • 功能
    Required for normal viability, growth and fertility.
  • 通路
    Amine and polyamine biosynthesis; spermine biosynthesis; spermine from spermidine: step 1/1.
  • 疾病相关
    Defects in SMS are the cause of Snyder-Robinson syndrome (SRS) [MIM:309583]; also known as X-linked mental retardation Snyder-Robinson type. SRS is characterized by moderate intellectual deficit, hypotonia, an unsteady gait, osteoporosis, kyphoscoliosis and facial asymmetry. Transmission is X-linked recessive.
  • 序列相似性
    Belongs to the spermidine/spermine synthase family.
  • 结构域
    Composed of 3 domains: the N-terminal domain has structural similarity to S-adenosylmethionine decarboxylase, the central domain is made up of four beta strands and the C-terminal domain is similar in structure to spermidine synthase. The N- and C-terminal domains are both required for activity.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE analysis of ab116763 at approximately 66.37kDa, stained with Coomassie Blue.

文献

ab116763 has not yet been referenced specifically in any publications.

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