Recombinant人SP110 protein (ab114669)

概述

  • 产品名称
    Recombinant人SP110 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      TPSDKKGKKRKRCIWSTPKRRHKKKSLPRGTASSRHGIQKKLKRVDQVPQ KKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPST PRRVTQGAAS
    • 分子量
      38 kDa including tags
    • 氨基酸
      271 to 380

技术指标

Our Abpromise guarantee covers the use of ab114669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • FLJ22835
    • IFI 41
    • IFI 75
    • IFI41
    • IFI75
    • Interferon induced protein 41
    • Interferon induced protein 41 30kD
    • Interferon induced protein 41/75
    • Interferon induced protein 75
    • Interferon induced protein 75 52kD
    • Interferon-induced protein 41/75
    • IPR 1
    • IPR1
    • Phosphoprotein 41
    • Phosphoprotein 75
    • SP 110
    • SP110
    • Sp110 nuclear body protein
    • SP110_HUMAN
    • Speckled 110 kDa
    • Transcriptional coactivator Sp110
    • VODI
    see all
  • 功能
    Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
  • 组织特异性
    Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 疾病相关
    Defects in SP110 are the cause of hepatic venoocclusive disease with immunodeficiency (VODI) [MIM:235550]. VODI is an autosomal recessive primary immunodeficiency associated with hepatic vascular occlusion and fibrosis. The immunodeficiency is characterized by severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absent lymph node germinal centers, and absent tissue plasma cells.
  • 序列相似性
    Contains 1 bromo domain.
    Contains 1 HSR domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 SAND domain.
  • 翻译后修饰
    Phosphorylated (isoform 2).
  • 细胞定位
    Nucleus. Found in the nuclear body.
  • Information by UniProt

Recombinant Human SP110 protein 图像

  • SDS-PAGE analysis of ab114669 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human SP110 protein (ab114669)参考文献

ab114669 has not yet been referenced specifically in any publications.

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