Recombinant人SP110 protein (ab114669)

概述

  • 产品名称Recombinant人SP110 protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionQ9HB58
    • 种属Human
    • 序列TPSDKKGKKRKRCIWSTPKRRHKKKSLPRGTASSRHGIQKKLKRVDQVPQ KKDDSTCNSTVETRAQKARTECARKSRSEEIIDGTSEMNEGKRSQKTPST PRRVTQGAAS
    • 分子量38 kDa including tags
    • 氨基酸271 to 380

相关产品

技术指标

Our Abpromise guarantee covers the use of ab114669 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • FLJ22835
    • IFI 41
    • IFI 75
    • IFI41
    • IFI75
    • Interferon induced protein 41
    • Interferon induced protein 41 30kD
    • Interferon induced protein 41/75
    • Interferon induced protein 75
    • Interferon induced protein 75 52kD
    • Interferon-induced protein 41/75
    • IPR 1
    • IPR1
    • Phosphoprotein 41
    • Phosphoprotein 75
    • SP 110
    • SP110
    • Sp110 nuclear body protein
    • SP110_HUMAN
    • Speckled 110 kDa
    • Transcriptional coactivator Sp110
    • VODI
    see all
  • 功能Transcription factor. May be a nuclear hormone receptor coactivator. Enhances transcription of genes with retinoic acid response elements (RARE).
  • 组织特异性Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
  • 疾病相关Defects in SP110 are the cause of hepatic venoocclusive disease with immunodeficiency (VODI) [MIM:235550]. VODI is an autosomal recessive primary immunodeficiency associated with hepatic vascular occlusion and fibrosis. The immunodeficiency is characterized by severe hypogammaglobulinemia, combined T and B cell immunodeficiency, absent lymph node germinal centers, and absent tissue plasma cells.
  • 序列相似性Contains 1 bromo domain.
    Contains 1 HSR domain.
    Contains 1 PHD-type zinc finger.
    Contains 1 SAND domain.
  • 翻译后修饰Phosphorylated (isoform 2).
  • 细胞定位Nucleus. Found in the nuclear body.
  • Information by UniProt

Recombinant Human SP110 protein 图像

  • SDS-PAGE analysis of ab114669 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human SP110 protein (ab114669)参考文献

ab114669 has not yet been referenced specifically in any publications.

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