The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
补充说明Protein concentration is above or equal to 0.05 mg/ml. Best used within three months from the date of receipt.
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
pH: 8.00 Constituents: 0.3% Glutathione, 0.79% Tris HCl
Na(+)/H(+) exchanger 3
Sodium/hydrogen exchanger 3
Sodium/hydrogen exchanger, apical epithelial
Solute carrier family 9 (sodium/hydrogen exchanger), isoform 3
Solute carrier family 9 (sodium/hydrogen exchanger), member 3
Solute carrier family 9 member 3
功能Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction.
序列相似性Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.
翻译后修饰Phosphorylated by PKA, which inhibits activity.
细胞定位Membrane. In intestinal epithelial cells, localizes to the ileal brush border.