Recombinant人SNX5 protein (ab40262)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab40262 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 纯度> 95 % SDS-PAGE.

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot. Store at -80°C. Avoid freeze / thaw cycle.

    Preservative: 0.002% Sodium Azide
    Constituents: 10mM Tris, 0.1% Triton X-100, pH 8

常规信息

  • 别名
    • 0910001N05Rik
    • 1810032P22Rik
    • AU019504
    • D2Ertd52e
    • FLJ10931
    • OTTHUMP00000030340
    • OTTHUMP00000062927
    • OTTMUSP00000003367
    • OTTMUSP00000003368
    • RP11-504H3.2
    • RP23-35E16.2
    • snoRNA MBI-43
    • SNX 5
    • SNX5
    • SNX5_HUMAN
    • Sorting nexin 5
    • Sorting nexin-5
    see all
  • 功能May be involved in several stages of intracellular trafficking. Plays a role in macropinocytosis. Plays a role in the internalization of EGFR after EGF stimulation.
  • 序列相似性Belongs to the sorting nexin family.
    Contains 1 BAR domain.
    Contains 1 PX (phox homology) domain.
  • 结构域The PX domain mediates interaction with membranes enriched in phosphatidylinositol 3,4-bisphosphate and/or phosphatidylinositol 4,5-bisphosphate.
  • 细胞定位Early endosome membrane. Cell membrane. Cytoplasmic vesicle membrane. Cytoplasm. Cell projection > phagocytic cup. Cell projection > ruffle. Recruited to the plasma membrane after EGF stimulation, which leads to increased levels of phosphatidylinositol 3,4-bisphosphate (PdtIns(3,4)P2). Detected on macropinosomes. Targeted to membrane ruffles in response to EGFR stimulation.
  • Information by UniProt

Recombinant Human SNX5 protein 图像

  • Analysis of SNX5 Recombinant Protein. 4-20% SDS gradient gel. Coomassie blue staining shows a band around 47kDa.

Recombinant Human SNX5 protein (ab40262)参考文献

ab40262 has not yet been referenced specifically in any publications.

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