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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
ab124986 is purified by proprietary chromatographic techniques.
ab124986 should be stored desiccated below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
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Shipped at 4°C. Store at -20°C. Store under desiccating conditions.
Constituents: 0.03% DTT, 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride
- FHA domain containing protein SNIP1
- FHA domain-containing protein SNIP1
Down-regulates NF-kappa-B signaling by competing with RELA for CREBBP/EP300 binding. Involved in the microRNA (miRNA) biogenesis.
Ubiquitous, with highest expression in heart and skeletal muscle.
Contains 1 FHA domain.
Degraded by the proteasome upon binding to the SMAD1/OAZ1/PSMB4 complex.
Phosphorylated upon DNA damage, probably by ATM or ATR.
Information by UniProt
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"