Recombinant人SNAPIN protein (ab81766)

概述

  • 产品名称
    Recombinant人SNAPIN protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MAGAGSAAVS GAGTPVAGPT GRDLFAEGLL EFLRPAVQQL DSHVHAVRES QVELREQIDN LATELCRINE DQKVALDLDP YVKKLLNARR RVVLVNNILQ NAQERLRRLN HSVAKETARR RAMLDSGIYP PGSPGK

技术指标

Our Abpromise guarantee covers the use of ab81766 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 90 % SDS-PAGE.
    ab81766 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 40% Glycerol, 0.2M Sodium chloride, 5mM DTT, 20mM Tris HCl, 2mM EDTA, pH 8.0

常规信息

  • 别名
    • OTTHUMP00000035157
    • SNAP associated protein
    • SNAP-25-binding protein
    • SNAP-associated protein
    • SNAP25BP
    • SNAPAP
    • Snapin
    • SNAPN_HUMAN
    • SNARE associated protein snapin
    • SNARE-associated protein Snapin
    • Synaptosomal associated protein 25 binding protein
    • Synaptosomal-associated protein 25-binding protein
    see all
  • 功能
    May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release by potentiating the interaction of synaptotagmins with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells.
  • 组织特异性
    Expressed in male germ cells of adult testis (at protein level).
  • 序列相似性
    Belongs to the SNAPIN family.
  • 发展阶段
    Expressed in germ cells of 22-week prenatal testis.
  • 细胞定位
    Cytoplasm. Membrane. Cytoplasmic vesicle membrane. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane. Cell junction > synapse > synaptosome. Cytoplasm > perinuclear region. May be cytoplasmic and peripheral membrane bound or anchored to the vesicular membrane through an N-terminal signal anchor (By similarity). Co-localizes with NANOS1 and PUM2 in the perinuclear region of germ cells.
  • Information by UniProt

图片

  • ab81766 on 15% SDS-PAGE (3µg)

文献

ab81766 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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