Recombinant人SMYD3 protein (ab125590)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus infected Sf9 cells
  • 氨基酸序列
    • AccessionQ9H7B4
    • 种属Human
    • 分子量71 kDa including tags
    • 氨基酸1 to 428

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技术指标

Our Abpromise guarantee covers the use of ab125590 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 7.50
    Constituents: 0.31% Glutathione, 0.002% PMSF, 0.004% DTT, 0.79% Tris HCl, 0.003% EDTA, 0.25% Glycerol, 0.88% Sodium chloride

常规信息

  • 别名
    • bA74P14.1
    • bA74P14.1 (novel protein)
    • FLJ21080
    • histone lysine N methyltransferase SMYD3
    • KMT3E
    • MGC104324
    • SET and MYND domain containing 3
    • SET and MYND domain containing protein 3
    • SET and MYND domain-containing protein 3
    • SMYD 3
    • Smyd3
    • SMYD3 protein
    • SMYD3_HUMAN
    • Zinc finger MYND domain containing 1
    • Zinc finger MYND domain containing protein 1
    • Zinc finger MYND domain-containing protein 1
    • Zinc finger protein subfamily 3A MYND domain containing 1
    • Zinc finger protein, subfamily 3A (MYND domain containing), 1
    • ZMYND 1
    • ZMYND1
    • ZNFN3A1
    see all
  • 功能Histone methyltransferase. Specifically methylates 'Lys-4' of histone H3, inducing di- and tri-methylation, but not monomethylation. Plays an important role in transcriptional activation as a member of an RNA polymerase complex. Binds DNA containing 5'-CCCTCC-3' or 5'-GAGGGG-3' sequences.
  • 组织特异性Expressed in skeletal muscles and testis. Overexpressed in a majority of colorectal and hepatocellular carcinomas.
  • 序列相似性Belongs to the histone-lysine methyltransferase family.
    Contains 1 MYND-type zinc finger.
    Contains 1 SET domain.
  • 细胞定位Cytoplasm. Nucleus. Mainly cytoplasmic when cells are arrested at G0/G1. Accumulates in the nucleus at S phase and G2/M.
  • Information by UniProt

Recombinant Human SMYD3 protein 图像

  • SDS page analysis of ab125590

Recombinant Human SMYD3 protein (ab125590)参考文献

ab125590 has not yet been referenced specifically in any publications.

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