Recombinant人Smoothened protein (ab112354)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      GPPPPLSHCGRAAPCEPLRYNVCLGSVLPYGATSTLLAGDSDSQEEAHGK LVLWSGLRNAPRCWAVIQPLLCAVYMPKCENDRVELPSRTLCQATRGPCA
    • 分子量
      37 kDa including tags
    • 氨基酸
      56 to 155
    • 标签
      GST tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab112354 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.31% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Frizzled family member 11
    • FZD11
    • Gx
    • Gx protein
    • Protein Gx
    • SMO
    • SMO_HUMAN
    • SMOH
    • Smoothened frizzled family receptor
    • Smoothened homolog
    • Smoothened homolog (Drosophila)
    • Smoothened homolog precursor (SMO) (Gx protein)
    • Smoothened seven transmembrane spanning receptor
    see all
  • 功能
    G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor patched is thought to prevent normal inhibition by patched of smoothened (SMO). Required for the accumulation of KIF7 and GLI3 in the cilia.
  • 序列相似性
    Belongs to the G-protein coupled receptor Fz/Smo family.
    Contains 1 FZ (frizzled) domain.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • ab112354 analysed on a 12.5% SDS-PAGE gel stained with Coomassie Blue.

文献

ab112354 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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