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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Constituents: 20mM Tris, pH 7.5
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
The mature N-terminus mediates interaction with XIAP.
Mitochondrion. Released into the cytosol when cells undergo apoptosis.
Information by UniProt
Recombinant Human Smac / Diablo protein 图像
Recombinant Human Smac / Diablo protein (ab87721)参考文献
has not yet been referenced specifically in any publications.
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