Full length protein
56 kDa including tags
1 to 239
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Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituent: 99% PBS
Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
The mature N-terminus mediates interaction with XIAP.
Mitochondrion. Released into the cytosol when cells undergo apoptosis.
Information by UniProt
has not yet been referenced specifically in any publications.
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