- 来源Escherichia coli
- 分子量56 kDa including tags
- 氨基酸1 to 239
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 90
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Constituent: 99% PBS
- 功能Promotes apoptosis by activating caspases in the cytochrome c/Apaf-1/caspase-9 pathway. Acts by opposing the inhibitory activity of inhibitor of apoptosis proteins (IAP).
- 组织特异性Ubiquitously expressed with highest expression in testis. Expression is also high in heart, liver, kidney, spleen, prostate and ovary. Low in brain, lung, thymus and peripheral blood leukocytes.
- 结构域The mature N-terminus mediates interaction with XIAP.
- 细胞定位Mitochondrion. Released into the cytosol when cells undergo apoptosis.
Information by UniProt
Recombinant Human Smac / Diablo protein 图像
Recombinant Human Smac / Diablo protein (ab116425)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"