重组人SLC26A3蛋白(ab116818)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      TQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFF RRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDT
    • 分子量
      36 kDa including tags
    • 氨基酸
      503 to 600

技术指标

Our Abpromise guarantee covers the use of ab116818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • Chloride anion exchanger
    • CLD
    • Congenital chloride diarrhea
    • Down regulated in adenoma
    • Down regulated in adenoma protein
    • Down-regulated in adenoma
    • DRA
    • Protein DRA
    • S26A3_HUMAN
    • SLC26A3
    • Solute carrier family 26 member 3
    see all
  • 功能
    Chloride/bicarbonate exchanger. Involved in absorbtion of in the colon. Helps mediate electrolyte and fluid absorption.
  • 疾病相关
    Defects in SLC26A3 are the cause of diarrhea type 1 (DIAR1) [MIM:214700]; also known as congenital chloride diarrhea (CLD). DIAR1 is a disease characterized by voluminous watery stools containing an excess of chloride. The children with this disease are often premature.
  • 序列相似性
    Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
    Contains 1 STAS domain.
  • 发展阶段
    Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Membrane.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE showing ab116818 at approximately 36.41kDa.
    Stained with Coomassie Blue.

文献

ab116818 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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