Recombinant人SLC26A3 protein (ab116818)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP40879
    • 种属Human
    • 序列TQFPKCSTLANIGRTNIYKNKKDYYDMYEPEGVKIFRCPSPIYFANIGFF RRKLIDAVGFSPLRILRKRNKALRKIRKLQKQGLLQVTPKGFICTVDT
    • 分子量36 kDa including tags
    • 氨基酸503 to 600

技术指标

Our Abpromise guarantee covers the use of ab116818 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • Chloride anion exchanger
    • CLD
    • Congenital chloride diarrhea
    • Down regulated in adenoma
    • Down regulated in adenoma protein
    • Down-regulated in adenoma
    • DRA
    • Protein DRA
    • S26A3_HUMAN
    • SLC26A3
    • Solute carrier family 26 member 3
    see all
  • 功能Chloride/bicarbonate exchanger. Involved in absorbtion of in the colon. Helps mediate electrolyte and fluid absorption.
  • 疾病相关Defects in SLC26A3 are the cause of diarrhea type 1 (DIAR1) [MIM:214700]; also known as congenital chloride diarrhea (CLD). DIAR1 is a disease characterized by voluminous watery stools containing an excess of chloride. The children with this disease are often premature.
  • 序列相似性Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
    Contains 1 STAS domain.
  • 发展阶段Expression is significantly decreased in adenomas (polyps) and adenocarcinomas of the colon.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human SLC26A3 protein 图像

  • 12.5% SDS-PAGE showing ab116818 at approximately 36.41kDa.
    Stained with Coomassie Blue.

Recombinant Human SLC26A3 protein (ab116818)参考文献

ab116818 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116818.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"