重组人Skp1蛋白(ab90687)
Key features and details
- Expression system: Escherichia coli
- Purity: > 90% SDS-PAGE
- Suitable for: SDS-PAGE, WB
描述
-
产品名称
重组人Skp1蛋白 -
纯度
> 90 % SDS-PAGE.
ab90687 is purified using conventional chromatography techniques. -
表达系统
Escherichia coli -
蛋白长度
Full length protein -
无动物成分
No -
性质
Recombinant -
-
种属
Human
-
相关产品
-
Related Products
技术指标
Our Abpromise guarantee covers the use of ab90687 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
-
应用
SDS-PAGE
Western blot
-
形式
Liquid -
Concentration information loading...
制备和贮存
-
稳定性和存储
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
pH: 8.00
Constituents: 0.316% Tris HCl, 10% Glycerol (glycerin, glycerine), 0.29% Sodium chloride
常规信息
-
别名
- Cyclin A/CDK2 associated p19
- Cyclin A/CDK2 associated protein p19
- Cyclin-A/CDK2-associated protein p19
see all -
功能
Essential component of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex, which mediates the ubiquitination of proteins involved in cell cycle progression, signal transduction and transcription. In the SCF complex, serves as an adapter that links the F-box protein to CUL1. SCF(BTRC) mediates the ubiquitination of NFKBIA at 'Lys-21' and 'Lys-22'; the degradation frees the associated NFKB1-RELA dimer to translocate into the nucleus and to activate transcription. SCF(Cyclin F) directs ubiquitination of CP110. -
通路
Protein modification; protein ubiquitination. -
序列相似性
Belongs to the SKP1 family. - Information by UniProt
图片
-
15% SDS-PAGE showing ab90687 (3µg).
实验方案
To our knowledge, customised protocols are not required for this product. Please try the standard protocols listed below and let us know how you get on.
数据表及文件
-
SDS download
-
Datasheet download
文献 (0)
ab90687 尚未被引用在任何文献中。