- 产品名称Recombinant人SIT protein
参阅全部 SIT 蛋白酶
- 蛋白长度Protein fragment
- 来源Escherichia coli
- 序列MGSSHHHHHHSSGLVPRGSHMHLSQWTRGRSRSHPGQGRSGESVEEVPLY GNLHYLQTGRLSQDPEPDQQDPTLGGPARAAEEVMCYTSLQLRPPQGRIP GPGTPVKYSEVVLDSEPKSQASGPEPELYASVCAQTRRARASFPDQAYAN SQPAAS
- 分子量17 kDa including tags
- 氨基酸62 to 196
- 标签His tag N-Terminus
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in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 纯度> 90
ab113580 is purified using conventional chromatography techniques.
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Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.
Constituents: 0.32% Tris HCl, 20% Glycerol
- SHP intracting transmembrane adapter protein
- SHP2-interacting transmembrane adapter protein
- 功能Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells. Involved in positive selection of T-cells.
- 组织特异性Specifically expressed in T- and B-cells. Present in plasma cells but not in germinal center B-cells (at protein level). Expressed in T- and B-cell lymphoma.
- 翻译后修饰Phosphorylated on tyrosines by LCK, FYN or ZAP70 upon TCR activation; which leads to the recruitment of PTPN11, GRB2 and CSK.
- 细胞定位Cell membrane.
Information by UniProt
Recombinant Human SIT protein 图像
Recombinant Human SIT protein (ab113580)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"