概述
- 产品名称Recombinant人SHP1 protein
参阅全部 SHP1 蛋白酶 - 蛋白长度Full length protein
描述
- 性质Recombinant
- 来源Escherichia coli
- 氨基酸序列
- 种属Human
相关产品
- Related Products
技术指标
Our Abpromise guarantee covers the use of ab61135 in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 应用
SDS-PAGE
Functional Studies
- 形式Liquid
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Concentration information loading...
制备和贮存
- 稳定性和存储
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: None
Constituents: 50% Sodium chloride, 30% Glycerol, 20mM MOPS, 0.25mM DTT, 0.1mM PMSF, pH 7.5This product is an active protein and may elicit a biological response in vivo, handle with caution.
常规信息
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别名
- 70Z-SHP
- EC 3.1.3.48
- HCP
see all - 功能Plays a key role in hematopoiesis. This PTPase activity may directly link growth factor receptors and other signaling proteins through protein-tyrosine phosphorylation. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against interacting substrates. Together with MTUS1, induces UBE2V2 expression upon angiotensin II stimulation.
- 组织特异性Isoform 1 is expressed in hematopoietic cells. Isoform 2 is expressed in non-hematopoietic cells.
- 序列相似性Belongs to the protein-tyrosine phosphatase family. Non-receptor class 2 subfamily.
Contains 2 SH2 domains.
Contains 1 tyrosine-protein phosphatase domain. - 翻译后修饰Phosphorylated on serine and tyrosine residues.
- 细胞定位Cytoplasm. Nucleus. In neurons, translocates into the nucleus after treatment with angiotensin II.
- Information by UniProt
Recombinant human SHP1 protein 图像
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Functional Studies - SHP1 protein (Tagged) (ab61135)Sample Kinase Activity Plot. -
SDS-PAGE - SHP1 protein (Tagged) (ab61135)ab61135 on SDS-PAGE, MW ~93 kDa.
Recombinant human SHP1 protein (ab61135)参考文献
ab61135 has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"