Recombinant人SH3GL2 protein (ab124551)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMGSHMSVAGLKKQFHKATQKVSEKVGGAEG TKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQPNPASRAKLSMINTMSK IRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEAMRELSE VKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQG KIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYH KQAVQILQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGG LSHTGTPKPSGVQMDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDEN WYEGMLHGHSGFFPINYVEILVALPH
    • 分子量
      43 kDa including tags
    • 氨基酸
      1 to 352
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab124551 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    > 90 % SDS-PAGE.
    Purified by using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Constituents: 0.02% DTT, 0.32% Tris HCl, 10% Glycerol, 0.29% Sodium chloride

常规信息

  • 别名
    • bA335L15.1 (SH3 domain GRB2 like 2)
    • CNSA2
    • EEN B1
    • EEN-B1
    • Endophilin 1
    • Endophilin A1
    • Endophilin A1 BAR domain
    • Endophilin-1
    • Endophilin-A1
    • FLJ20276
    • FLJ25015
    • OTTHUMP00000021084
    • SH3 domain containing GRB2 like protein 2
    • SH3 domain GRB2 like 2
    • SH3 domain protein 2A
    • SH3 domain-containing GRB2-like protein 2
    • SH3D2A
    • SH3G2_HUMAN
    • Sh3gl2
    • Sh3p4
    • SH3PA
    see all
  • 功能
    Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
  • 组织特异性
    Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum.
  • 序列相似性
    Belongs to the endophilin family.
    Contains 1 BAR domain.
    Contains 1 SH3 domain.
  • 结构域
    An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes. The BAR domain dimer forms a rigid crescent shaped bundle of helices with the pair of second amphipathic helices protruding towards the membrane-binding surface.
  • 细胞定位
    Cytoplasm. Membrane. Concentrated in presynaptic nerve terminals in neurons.
  • Information by UniProt

图片

  • 15% SDS-PAGE (3 µg loaded)

文献

ab124551 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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