Recombinant人SH3GL2 protein (ab116741)

概述

描述

  • 性质
    Recombinant
  • 来源
    Wheat germ
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEI MTKTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKF GRELGDDCNFGPALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKD LREIQHHLKKLEGRRLDFDYKKKRQGKIPDEELRQALEKFDESKEIAESS MFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRLEERIRQASSQ PRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQPCCRALYD FEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVAL PH
    • 分子量
      65 kDa including tags
    • 氨基酸
      1 to 352

技术指标

Our Abpromise guarantee covers the use of ab116741 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    ELISA

    Western blot

  • 形式
    Liquid
  • 补充说明
    Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.79% Tris HCl, 0.3% Glutathione

常规信息

  • 别名
    • bA335L15.1 (SH3 domain GRB2 like 2)
    • CNSA2
    • EEN B1
    • EEN-B1
    • Endophilin 1
    • Endophilin A1
    • Endophilin A1 BAR domain
    • Endophilin-1
    • Endophilin-A1
    • FLJ20276
    • FLJ25015
    • OTTHUMP00000021084
    • SH3 domain containing GRB2 like protein 2
    • SH3 domain GRB2 like 2
    • SH3 domain protein 2A
    • SH3 domain-containing GRB2-like protein 2
    • SH3D2A
    • SH3G2_HUMAN
    • Sh3gl2
    • Sh3p4
    • SH3PA
    see all
  • 功能
    Implicated in synaptic vesicle endocytosis. May recruit other proteins to membranes with high curvature.
  • 组织特异性
    Brain, mostly in frontal cortex. Expressed at high level in fetal cerebellum.
  • 序列相似性
    Belongs to the endophilin family.
    Contains 1 BAR domain.
    Contains 1 SH3 domain.
  • 结构域
    An N-terminal amphipathic helix, the BAR domain and a second amphipathic helix inserted into helix 1 of the BAR domain (N-BAR domain) induce membrane curvature and bind curved membranes. The BAR domain dimer forms a rigid crescent shaped bundle of helices with the pair of second amphipathic helices protruding towards the membrane-binding surface.
  • 细胞定位
    Cytoplasm. Membrane. Concentrated in presynaptic nerve terminals in neurons.
  • Information by UniProt

图片

  • 12.5% SDS-PAGE of ab116741 at approximately 64.79kDa stained with Coomassie Blue.

文献

ab116741 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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