Recombinant人SGLT2 protein (ab114508)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP31639
    • 种属Human
    • 序列GLFDKYLGAATSLTVSEDPAVGNISSFCYRPRPDSYHLLRHPVTGDLPWP
    • 分子量31 kDa including tags
    • 氨基酸228 to 277

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技术指标

Our Abpromise guarantee covers the use of ab114508 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. This protein is best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Low affinity sodium glucose cotransporter
    • Low affinity sodium-glucose cotransporter
    • Na(+) glucose cotransporter 2
    • Na(+)/glucose cotransporter 2
    • OTTHUMP00000163298
    • SC5A2_HUMAN
    • SGLT 2
    • SLC5A 2
    • SLC5A2
    • Sodium glucose cotransporter 2
    • Sodium/glucose cotransporter 2
    • Solute carrier family 5 (sodium glucose cotransporter) member 2
    • Solute carrier family 5 (sodium/glucose transporter), member 2
    • Solute carrier family 5 member 2
    see all
  • 功能Sodium-dependent glucose transporter. Has a Na(+) to glucose coupling ratio of 1:1.
    Efficient substrate transport in mammalian kidney is provided by the concerted action of a low affinity high capacity and a high affinity low capacity Na(+)/glucose cotransporter arranged in series along kidney proximal tubules.
  • 疾病相关Defects in SLC5A2 are the cause of renal glucosuria (GLYS1) [MIM:233100]. GLYS1 is an autosomal recessive disorder characterized by a normal fasting serum glucose concentration and persistent isolated glucosuria, with a normal glucose tolerance test.
  • 序列相似性Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human SGLT2 protein 图像

  • ab114508 analysed by 12.5% SDS-PAGE and stained with Coomassie Blue.

Recombinant Human SGLT2 protein (ab114508)参考文献

ab114508 has not yet been referenced specifically in any publications.

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