Recombinant人Seryl-tRNA synthetase protein (ab116885)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP49591
    • 种属Human
    • 序列MVLDLDLFRVDKGGDPALIRETQEKRFKDPGLVDQLVKADSEWRRCRFRA DNLNKLKNLCSKTIGEKMKKKEPVGDDESVPENVLSFDDLTADALANLKV SQIKKVRLLIDEAILKCDAERIKLEAERFENLREIGNLLHPSVPISNDED VDNKVERIWGDCTVRKKYSHVDLVVMVDGFEGEKGAVVAGSRGYFLKGVL VFLEQALIQYALRTLGSRGYIPIYTPFFMRKEVMQEVAQLSQFDEELYKV IGKGSEKSDDNSYDEKYLIATSEQPIAALHRDEWLRPEDLPIKYAGLSTC FRQEVGSHGRDTRGIFRVHQFEKIEQFVYSSPHDNKSWEMFEEMITTAEE FYQSLGIPYHIVNIVSGSLNHAASKKLDLEAWFPGSGAFRELVSCSNCTD YQARRLRIRYGQTKKMMDKVEFVHMLNATMCATTRTICAILENYQTEKGI TVPEKLKEFMPPGLQELIPFVKPAPIEQEPSKKQKKQHEGSKKKAAARDV TLENRLQNMEVTDA
    • 分子量83 kDa including tags
    • 氨基酸1 to 515

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技术指标

Our Abpromise guarantee covers the use of ab116885 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    Western blot

    SDS-PAGE

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml. Best use within three months from the date of receipt of this protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • C78314
    • cytoplasmic
    • EC 6.1.1.11
    • FLJ36399
    • sarS
    • Sars1
    • Serine tRNA ligase
    • Serine tRNA ligase 1, cytoplasmic
    • Serine--tRNA ligase
    • serine--tRNA ligase, cytoplasmic
    • SerRS
    • SERS
    • Seryl tRNA Ser/Sec synthetase
    • Seryl tRNA synthetase
    • Seryl tRNA synthetase cytoplasmic
    • Seryl-tRNA Ser/Sec synthetase
    • Seryl-tRNA synthetase
    • seryl-tRNA synthetase, cytoplasmic
    • Seryl-tRNA(Ser/Sec) synthetase
    • Strs
    • SYSC_HUMAN
    see all
  • 功能Catalyzes the attachment of serine to tRNA(Ser). Is also probably able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
  • 通路Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.
  • 序列相似性Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.
  • 结构域Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.
  • 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human Seryl-tRNA synthetase protein 图像

  • 12.5% SDS-PAGE showing ab116885 at approximately 82.65kDa, stained with Coomassie Blue.

Recombinant Human Seryl-tRNA synthetase protein (ab116885)参考文献

ab116885 has not yet been referenced specifically in any publications.

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