Recombinant人Serum Amyloid A protein (ab50232)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP0DJI8
    • 种属Human
    • 序列MRSFFSFLGE AFDGARDMWR AYSDMREANY IGSDKYFHAR GNYDAAKRGP GGVWAAEAIS NARENIQRFF GRGAEDSLAD QAANEWGRSG KDPNHFRPAG LPEKY
    • 分子量12 kDa
    • 修饰unmodified N60 + R71

技术指标

Our Abpromise guarantee covers the use of ab50232 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性

    Tested by its ability to down- regulate lipid biosynthesis in aortic smooth muscle cells. The effective concentration was found to be 4 μM. Schreiber, BM. et al. Biochem J. 1999 Nov 15; 344 Pt 1:7-13

  • 应用

    SDS-PAGE

    Functional Studies

    Western blot

  • 内毒素水平< 0.100 Eu/µg
  • 纯度> 98 % SDS-PAGE.
    Greater than 98% by SDS-PAGE and HPLC analyses.
  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.

    Preservative: None
    Endotoxin level is less than 0.1 ng per µg (1EU/µg).

    This product is an active protein and may elicit a biological response in vivo, handle with caution.

  • 复溶Please reconstitute this product in water to a concentration of 1mg/ml.

常规信息

  • 别名
    • Amyloid fibril protein AA
    • Amyloid fibrils
    • Amyloid protein A
    • Fibrils
    • MGC111216
    • OC
    • PIG 4
    • PIG4
    • SAA
    • SAA 1
    • SAA 2
    • SAA_HUMAN
    • SAA1
    • SAA2
    • Serum amyloid A protein precursor
    • Serum amyloid A1 isoform 1
    • Serum amyloid A1 isoform 2
    • Serum amyloid protein A(4-101)
    • TP53I4
    • Tumor protein p53 inducible protein 4
    see all
  • 功能Major acute phase reactant. Apolipoprotein of the HDL complex.
  • 组织特异性Expressed by the liver; secreted in plasma.
  • 疾病相关Note=Reactive, secondary amyloidosis is characterized by the extracellular accumulation in various tissues of the SAA protein. These deposits are highly insoluble and resistant to proteolysis; they disrupt tissue structure and compromise function.
    Note=Elevated serum SSA protein levels may be associated with lung cancer.
  • 序列相似性Belongs to the SAA family.
  • 翻译后修饰This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
  • 细胞定位Secreted.
  • Information by UniProt

Recombinant human Serum Amyloid A protein 图像

  • Anti-Serum Amyloid A antibody [115] (ab687) at 0.5 µg/ml + Recombinant human Serum Amyloid A protein (ab50232) at 0.01 µg

    Secondary
    Goat Anti-Mouse IgG H&L (HRP) preadsorbed (ab97040) at 1/5000 dilution
    Developed using the ECL technique

    Performed under reducing conditions.

    Exposure time : 1 minute

Recombinant human Serum Amyloid A protein (ab50232)参考文献

ab50232 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"