Recombinant人Serine racemase protein (ab116196)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHHSSGLVPRGSHMGSHMCAQYCISFADVEKAHINIRDSIHLT PVLTSSILNQLTGRNLFFKCELFQKTGSFKIRGALNAVRSLVPDALERKP KAVVTHSSGNHGQALTYAAKLEGIPAYIVVPQTAPDCKKLAIQAYGASIV YCEPSDESRENVAKRVTEETEGIMVHPNQEPAVIAGQGTIALEVLNQVPL VDALVVPVGGGGMLAGIAITVKALKPSVKVYAAEPSNADDCYQSKLKGKL MPNLYPPETIADGVKSSIGLNTWPIIRDLVDDIFTVTEDEIKCATQLVWE RMKLLIEPTAGVGVAAVLSQHFQTVSPEVKNICIVLSGGNVDLTSSITWV KQAERPASYQSVSV
    • 分子量
      39 kDa including tags
    • 氨基酸
      1 to 340
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab116196 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度
    > 85 % SDS-PAGE.
    ab116196 was purified using conventional chromatography.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 20% Glycerol, 0.58% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • D serine ammonia lyase
    • D serine dehydratase
    • D-serine ammonia-lyase
    • D-serine dehydratase
    • ILV1
    • ISO1
    • L serine ammonia lyase
    • L serine dehydratase
    • L-serine ammonia-lyase
    • L-serine dehydratase
    • Serine racemase
    • srr
    • SRR_HUMAN
    see all
  • 功能
    Catalyzes the synthesis of D-serine from L-serine. D-serine is a key coagonist with glutamate at NMDA receptors. Has dehydratase activity towards both L-serine and D-serine.
  • 组织特异性
    Brain: expressed at high levels in hippocampus and corpus callosum, intermediate levels in substantia nigra and caudate, and low levels in amygdala, thalamus, and subthalamic nuclei. Expressed in heart, skeletal muscle, kidney and liver.
  • 序列相似性
    Belongs to the serine/threonine dehydratase family.
  • 翻译后修饰
    S-nitrosylated, leading to decrease the enzyme activity.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of 3 µg ab116196.

文献

ab116196 has not yet been referenced specifically in any publications.

客户评价及客户问答

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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