Recombinant人Scramblase 1 protein (ab114676)

概述

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionO15162
    • 种属Human
    • 序列MDKQNSQMNASHPETNLPVGYPPQYPPTAFQGPPGYSGYPGPQVSYPPPP AGHSGPGPAGFPVPNQPVYNQPVYNQPVGAAGVPWMPAPQPPLNCPPGLE YLSQIDQILIHQQIELLEVLTGFETNNKYEIKNSFGQRVYFAAEDTDCCT RNCCGPSRPFTLRIIDNMGQEVITLERPLRCSSCCCPCCLQEIEIQAPPG VPIGYVIQTWHPCLPKFTIQNEKREDVLKISGPCVVCSCCGDVDFEIKSL DEQCVVGKISKHWTGILREAFTDADNFGIQFPLDLDVKMKAVMIGACFLI DFMFFESTGSQEQKSGVW
    • 分子量61 kDa including tags
    • 氨基酸1 to 318

技术指标

Our Abpromise guarantee covers the use of ab114676 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

    ELISA

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • Ca(2+) dependent phospholipid scramblase 1
    • Ca(2+)-dependent phospholipid scramblase 1
    • Erythrocyte phospholipid scramblase
    • MM1 cell-derived transplantability-associated gene 1b, mouse, homolog of
    • MmTRA1a
    • MmTRA1b
    • Nor1
    • Phospholipid scramblase 1
    • PL scramblase 1
    • PLS1_HUMAN
    • PLSCR 1
    • Plscr1
    • Scramblase1
    • Tra1
    • Tra1a
    • Tra1b
    • Transplantability-associated protein 1
    • Tras1
    • Tras2
    see all
  • 功能May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.
    May play a role in the antiviral response of interferon (IFN) by amplifying and enhancing the IFN response through increased expression of select subset of potent antiviral genes. May contribute to cytokine-regulated cell proliferation and differentiation.
  • 组织特异性Expressed in platelets, erythrocyte membranes, lymphocytes, spleen, thymus, prostate, testis, uterus, intestine, colon, heart, placenta, lung, liver, kidney and pancreas. Not detected in brain and skeletal muscle.
  • 序列相似性Belongs to the phospholipid scramblase family.
  • 翻译后修饰Known to be palmitoylated at one, yet undefined, site.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human Scramblase 1 protein 图像

  • SDS-PAGE analysis of ab114676 on a 12.5% gel stained with Coomassie Blue.

Recombinant Human Scramblase 1 protein (ab114676)参考文献

ab114676 has not yet been referenced specifically in any publications.

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