Recombinant人SC35 protein (ab82083)

概述

描述

  • 性质Recombinant
  • 来源Baculovirus
  • 氨基酸序列
    • 种属Human

技术指标

Our Abpromise guarantee covers the use of ab82083 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 生物活性1 unit equals 1 nanogram of purified protein.
  • 应用

    SDS-PAGE

  • 形式Liquid
  • 补充说明1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.00584% EDTA, 0.476% HEPES, 0.0077% DTT, 0.55% Ammonium sulphate, 20% Glycerol

常规信息

  • 别名
    • 35 kDa
    • arginine/serine-rich 2
    • PR264
    • Protein PR264
    • SC 35
    • SC-35
    • SC35
    • Serine/arginine-rich splicing factor 2
    • SFRS 2
    • SFRS2
    • SFRS2A
    • Splicing component
    • Splicing component 35 kDa
    • Splicing factor
    • Splicing factor arginine/serine rich 2
    • Splicing factor SC35
    • Splicing speckle
    • Splicing speckles
    • SR splicing factor 2
    • SRp30b
    • SRSF2
    • SRSF2_HUMAN
    see all
  • 功能Necessary for the splicing of pre-mRNA. It is required for formation of the earliest ATP-dependent splicing complex and interacts with spliceosomal components bound to both the 5'- and 3'-splice sites during spliceosome assembly. It also is required for ATP-dependent interactions of both U1 and U2 snRNPs with pre-mRNA. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5'- and 3'-splice site binding components, U1 snRNP and U2AF. Binds to purine-rich RNA sequences, either 5'-AGSAGAGTA-3' (S=C or G) or 5'-GTTCGAGTA-3'. Can bind to beta-globin mRNA and commit it to the splicing pathway.
  • 序列相似性Belongs to the splicing factor SR family.
    Contains 1 RRM (RNA recognition motif) domain.
  • 翻译后修饰Extensively phosphorylated on serine residues in the RS domain.
  • 细胞定位Nucleus.
  • Information by UniProt

Recombinant Human SC35 protein (ab82083)参考文献

ab82083 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"