Recombinant人S100A12 protein (ab103393)

概述

  • 产品名称Recombinant人S100A12 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP80511
    • 种属Human
    • 序列MKHHHHHHAS TKLEEHLEGI VNIFHQYSVR KGHFDTLSKG ELKQLLTKEL ANTIKNIKDK AVIDEIFQGL DANQDEQVDF QEFISLVAIA LKAAHYHTHK E
    • 分子量12 kDa including tags
    • 氨基酸2 to 92
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab103393 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Western blot

  • 形式Lyophilised
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 20mM Tris, pH 7.5

  • 复溶Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Filter the product by an appropriate sterile filter before using it in the cell culture.

常规信息

  • 别名
    • CAAF1
    • CAGC
    • Calcitermin
    • Calcium-binding protein in amniotic fluid 1
    • Calgranulin C
    • Calgranulin-C
    • Calgranulin-related protein
    • CGRP
    • EN RAGE
    • EN-RAGE
    • ENRAGE
    • Extracellular newly identified RAGE-binding protein
    • migration inhibitory factor-related protein 6
    • MRP6
    • Neutrophil S100 protein
    • p6
    • Protein S100 A12
    • S100 calcium binding protein A12
    • S100 calcium-binding protein A12
    • S100 calcium-binding protein A12 (calgranulin C)
    • S100A12
    • S10AC_HUMAN
    see all
  • 功能Calcitermin possesses antifungal activity against C.albicans and is also active against E.coli and P.aeruginosa but not L.monocytogenes and S.aureus. Binds calcium, zinc and copper. Presence of zinc increases the affinity for calcium. Plays an important role in the inflammatory response. Interaction with AGER on endothelium, mononuclear phagocytes, and lymphocytes triggers cellular activation, with generation of key proinflammatory mediators.
  • 组织特异性Monocytes and lymphocytes.
  • 序列相似性Belongs to the S-101 family.
    Contains 2 EF-hand domains.
  • Information by UniProt

Recombinant Human S100A12 protein 图像

  • 14% SDS-PAGE analysis of 5 µg ab103393
    Lane 1: reduced and heated sample
    Lane 2: non reduced and non heated sample

Recombinant Human S100A12 protein (ab103393)参考文献

This product has been referenced in:
  • Lorenzi R  et al. Soluble form of receptor for advanced glycation end-products (sRAGE): do sRAGE ligands or anti-sRAGE auto-antibodies interfere with sRAGE quantification? Ann Clin Biochem N/A:N/A (2013). Read more (PubMed: 23982266) »

See 1 Publication for this product

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"