Recombinant人S100 calcium binding protein A14 (ab101041)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ9HCY8
    • 种属Human
    • 序列MKHHHHHHASMGQCRSANAEDAQEFSDVERAIETLIKNFHQYSVEGGKET LTPSELRDLVTQQLPHLMPSNCGLEEKIANLGSCNDSKLEFRSFWELIGE AAKSVKLERPVRGH
    • 分子量13 kDa including tags
    • 氨基酸1 to 104
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101041 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Western blot

    SDS-PAGE

  • 形式Lyophilised
  • 补充说明Store lyophilized protein at –20°C. Lyophilized protein remains stable until the expiry date when stored at –20°C. Aliquot reconstituted protein to avoid repeated freezing/thawing cycles and store at –80°C for long term storage. Reconstituted protein can be stored at 4°C for a limited period of time; it does not show any change after one week at 4°C.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 50mM Sodium chloride, 20mM Tris, pH 7.5

  • 复溶Add deionized water to prepare a working stock solution of approximately 0.5 mg/mL and let the lyophilized pellet dissolve completely. Product is not sterile! Please filter the product by an appropriate sterile filter before using it in cell culture.

常规信息

  • 别名
    • BCMP84
    • Protein S100-A14
    • S100 calcium binding protein A14
    • S100 calcium-binding protein A14
    • S100a14
    • S100A15
    • S10AE_HUMAN
    • S114
    see all
  • 功能Modulates P53/TP53 protein levels, and thereby plays a role in the regulation of cell survival and apoptosis. Depending on the context, it can promote cell proliferation or apoptosis. Plays a role in the regulation of cell migration by modulating the levels of MMP2, a matrix protease that is under transcriptional control of P53/TP53. Does not bind calcium.
  • 组织特异性Expressed at highest levels in colon and at moderate levels in thymus, kidney, liver, small intestine, and lung. Low expression in heart and no expression is seen in brain, skeletal muscle, spleen, placenta and peripheral blood leukocytes.
  • 序列相似性Belongs to the S-100 family.
    Contains 1 EF-hand domain.
  • 细胞定位Cytoplasm.
  • Information by UniProt

Recombinant Human S100 calcium binding protein A14 图像

  • 14% SDS-PAGE analysis of ab101041
    Lane 1: Molecular weight markers; 14, 21, 31, 45, 66, 97 kDa
    Lane 2: ab101041 (reduced and heated, 5µg / lane)
    Lane 3: ab101041 (non-reduced and non-heated, 5µg / lane).

Recombinant Human S100 calcium binding protein A14 (ab101041)参考文献

ab101041 has not yet been referenced specifically in any publications.

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