Recombinant人RUNX3 protein (ab95893)

概述

  • 产品名称
    Recombinant人RUNX3 protein
  • 蛋白长度
    Protein fragment

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MRSMVDVLAD HAGELVRTDS PNFLCSVLPS HWRCNKTLPV AFKVVALGDV PDGTVVTVMA GNDENYSAEL RNASAVMKNQ VARFNDLRFV GRSGRGKSFT LTITVFTNPT QVATYHRAIK VTVDGPREPR RHRQK
    • 分子量
      17 kDa including tags
    • 氨基酸
      53 to 186
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab95893 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF-TOF
  • 纯度
    > 95 % SDS-PAGE.
    ab95893 is purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 20% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0

常规信息

  • 别名
    • Acute myeloid leukemia 2 protein
    • Acute myeloid leukemia gene 2
    • AML 2
    • AML2
    • CBF alpha 3
    • CBF-alpha-3
    • CBFA 3
    • CBFA3
    • core binding factor
    • Core binding factor alpha 3 subunit
    • Core binding factor runt domain alpha subunit 3
    • Core binding factor subunit alpha 3
    • core-binding factor
    • Core-binding factor subunit alpha-3
    • Oncogene AML 2
    • Oncogene AML-2
    • PEA2 alpha C
    • PEA2-alpha C
    • PEBP2 alpha C
    • PEBP2-alpha C
    • Pebp2a3
    • PEBP2aC
    • Polyomavirus enhancer binding protein 2 alpha C subunit
    • Polyomavirus enhancer-binding protein 2 alpha C subunit
    • runt domain alpha subunit 3
    • runt related transcription factor 3
    • Runt-related transcription factor 3
    • RUNX 3
    • Runx3
    • RUNX3_HUMAN
    • SL3 3 enhancer factor 1 alpha C subunit
    • SL3-3 enhancer factor 1 alpha C subunit
    • SL3/AKV core binding factor alpha C subunit
    • SL3/AKV core-binding factor alpha C subunit
    • Transcription factor AML2
    see all
  • 功能
    CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, lck, IL-3 and GM-CSF promoters.
  • 序列相似性
    Contains 1 Runt domain.
  • 结构域
    A proline/serine/threonine rich region at the C-terminus is necessary for transcriptional activation of target genes.
  • 翻译后修饰
    Phosphorylated on tyrosine residues by SRC. Phosphorylated by LCK and FYN.
  • 细胞定位
    Nucleus. Cytoplasm. The tyrosine phosphorylated form localizes to the cytoplasm.
  • Information by UniProt

图片

  • 15% SDS-PAGE showing ab95893 at approximately 17.1kDa (3µg).

文献

ab95893 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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