Recombinant人RRM2 protein (ab99137)

概述

  • 产品名称
    Recombinant人RRM2 protein
  • 蛋白长度
    Full length protein

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • Accession
    • 种属
      Human
    • 序列
      MGSSHHHHHH SSGLVPRGSH MLSLRVPLAP ITDPQQLQLS PLKGLSLVDK ENTPPALSGT RVLASKTARR IFQEPTEPKT KAAAPGVEDEPLLRENPRRF VIFPIEYHDI WQMYKKAEAS FWTAEEVDLS KDIQHWESLK PEERYFISHV LAFFAASDGI VNENLVERFS QEVQITEARC FYGFQIAMEN IHSEMYSLLI DTYIKDPKER EFLFNAIETM PCVKKKADWA LRWIGDKEAT YGERVVAFAA VEGIFFSGSF ASIFWLKKRGLMPGLTFSNE LISRDEGLHC DFACLMFKHL VHKPSEERVR EIIINAVRIE QEFLTEALPV KLIGMNCTLM KQYIEFVADR LMLELGFSKV FRVENPFDFM ENISLEGKTN FFEKRVGEYQ RMGVMSSPTE NSFTLDADF
    • 分子量
      47 kDa including tags
    • 氨基酸
      1 to 389
    • 标签
      His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab99137 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度
    >= 85 % SDS-PAGE.
    ab99137 was purified using conventional chromatography techniques.
  • 形式
    Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    Preservative: None
    Constituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8

常规信息

  • 别名
    • cb111
    • chunp6884
    • etID309896.20
    • R2
    • reductase M2 polypeptide variant 1
    • reductase M2 polypeptide variant 2
    • reductase M2 polypeptide variant 3a
    • reductase M2 polypeptide variant 3b
    • reductase M2 polypeptide variant 3c
    • reductase M2 polypeptide variant 3d
    • Ribonucleoside-diphosphate reductase subunit M2
    • Ribonucleotide reductase M2
    • Ribonucleotide reductase M2 polypeptide
    • Ribonucleotide reductase M2 subunit
    • ribonucleotide reductase protein r2 class I
    • Ribonucleotide reductase regulatory subunit M2
    • Ribonucleotide reductase small chain
    • Ribonucleotide reductase small subunit
    • Ribonucleotide reductase, R2 subunit
    • RIR2_HUMAN
    • RR2
    • RR2M
    • RRM2
    see all
  • 功能
    Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. Inhibits Wnt signaling.
  • 通路
    Genetic information processing; DNA replication.
  • 序列相似性
    Belongs to the ribonucleoside diphosphate reductase small chain family.
  • 翻译后修饰
    Phosphorylation on Ser-20 relieves the inhibitory effect on Wnt signaling.
  • 细胞定位
    Cytoplasm.
  • Information by UniProt

图片

  • 15% SDS-PAGE analysis of ab99137 (3ug)

文献

ab99137 has not yet been referenced specifically in any publications.

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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"

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