Recombinant人RRAD protein (ab114746)

概述

  • 产品名称Recombinant人RRAD protein
  • 蛋白长度Protein fragment

描述

  • 性质Recombinant
  • 来源Wheat germ
  • 氨基酸序列
    • AccessionP55042
    • 种属Human
    • 序列VYKVLLLGAPGVGKSALARIFGGVEDGPEAEAAGHTYDRSIVVDGEEASL MVYDIWEQDGGRWLPGHCMAMGDAYVIVYSVTDKGSFEKASELRVQLRRA RQTDDVPIIL
    • 分子量38 kDa including tags
    • 氨基酸91 to 200

技术指标

Our Abpromise guarantee covers the use of ab114746 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    ELISA

    SDS-PAGE

    Western blot

  • 形式Liquid
  • 补充说明Protein concentration is above or equal to 0.05 mg/ml.
    Best used within three months from the date of receipt.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    pH: 8.00
    Constituents: 0.3% Glutathione, 0.79% Tris HCl

常规信息

  • 别名
    • GTP binding protein RAD
    • GTP-binding protein RAD
    • RAD
    • RAD_HUMAN
    • RAD1
    • RAS (RAD and GEM) like GTP binding 3
    • Ras associated with diabetes
    • Ras related associated with diabetes
    • REM3
    • RRAD
    see all
  • 功能May play an important role in cardiac antiarrhythmia via the strong suppression of voltage-gated L-type Ca(2+) currents. Regulates voltage-dependent L-type calcium channel subunit alpha-1C trafficking to the cell membrane (By similarity). Inhibits cardiac hypertrophy through the calmodulin-dependent kinase II (CaMKII) pathway. Inhibits phosphorylation and activation of CAMK2D.
  • 组织特异性Most abundantly expressed in the heart. Also found in the skeletal muscle and lung. Lesser amounts in placenta and kidney. Also detected in adipose tissue. Overexpressed in muscle of type II diabetic humans.
  • 序列相似性Belongs to the small GTPase superfamily. RGK family.
  • 细胞定位Cell membrane.
  • Information by UniProt

Recombinant Human RRAD protein 图像

  • 12.5% SDS-PAGE showing ab114746 at approximately 37.73kDa.
    Stained with Coomassie Blue.

Recombinant Human RRAD protein (ab114746)参考文献

ab114746 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab114746.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"