Recombinant人RPIA protein (ab116207)

概述

  • 产品名称Recombinant人RPIA protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP49247
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMQRPGPFSTLYGRVLAPLPGRAGGAASGGG GNSWDLPGSHVRLPGRAQSGTRGGAGNTSTSCGDSNSICPAPSTMSKAEE AKKLAGRAAVENHVRNNQVLGIGSGSTIVHAVQRIAERVKQENLNLVCIP TSFQARQLILQYGLTLSDLDRHPEIDLAIDGADEVDADLNLIKGGGGCLT QEKIVAGYASRFIVIADFRKDSKNLGDQWHKGIPIEVIPMAYVPVSRAVS QKFGGVVELRMAVNKAGPVVTDNGNFILDWKFDRVHKWSEVNTAIKMIPG VVDTGLFINMAERVYFGMQDGSVNMREKPFC
    • 分子量35 kDa including tags
    • 氨基酸1 to 311
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab116207 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    Mass Spectrometry

    SDS-PAGE

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab116207 was purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 0.03% DTT, 40% Glycerol, 1.17% Sodium chloride, 0.06% EDTA, 0.004% PMSF

常规信息

  • 别名
    • EC 5.3.1.6
    • MGC103524
    • Phosphoriboisomerase
    • Phosphoriboisomerase A
    • Ribose 5 phosphate isomerase
    • ribose 5-phosphate epimerase
    • ribose 5-phosphate isomerase A
    • Ribose-5-phosphate isomerase
    • RPI
    • rpiA
    • RPIA_HUMAN
    • zgc:103524
    see all
  • 通路Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
  • 疾病相关Defects in RPIA are the cause of ribose 5-phosphate isomerase deficiency (RPID) [MIM:608611]. A patient has been described with a deficiency of ribose 5-phosphate isomerase who presented with leukoencephalopathy and peripheral neuropathy. Proton magnetic resonance spectroscopy of the brain revealed a highly elevated level of the polyols ribitol and D-arabitol, which were subsequently also found in high concentrations in body fluids. Deficient activity of RPIA, one of the pentose phosphate pathway enzymes, has been demonstrated in fibroblasts.
  • 序列相似性Belongs to the ribose 5-phosphate isomerase family.
  • Information by UniProt

Recombinant Human RPIA protein 图像

  • 15% SDS-PAGE analysis of 3 µg ab116207.

Recombinant Human RPIA protein (ab116207)参考文献

ab116207 has not yet been referenced specifically in any publications.

Product Wall

There are currently no Abreviews or Questions for ab116207.
Please use the links above to contact us or submit feedback about this product.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"