- 来源Baculovirus infected Sf9 cells
- 分子量66 kDa including tags
- 氨基酸5 to 554
- 标签His tag N-Terminus
- Related Products
- Substrate reagent
Our Abpromise guarantee covers the use of
in the following tested applications.
The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.
- 生物活性The specific activity of ab125828 was determined to be 605 nmol/min/mg.
- 纯度> 95
Purity was determined to be >95% by densitometry.
ab204880 (RPS6 peptide) can be utilized as a substrate for assessing kinase activity
Concentration information loading...
Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.
Preservative: 1.02% Imidazole
Constituents: 0.002% PMSF, 0.71% Sodium phosphate, 0.004% DTT, 25% Glycerol, 1.75% Sodium chloride
This product is an active protein and may elicit a biological response in vivo, handle with caution.
- coiled-coil-containing protein kinase 2
- p164 ROCK 2
- 功能Regulates the assembly of the actin cytoskeleton. Promotes formation of stress fibers and of focal adhesion complexes. Plays a role in smooth muscle contraction.
- 序列相似性Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
Contains 1 AGC-kinase C-terminal domain.
Contains 1 PH domain.
Contains 1 phorbol-ester/DAG-type zinc finger.
Contains 1 protein kinase domain.
Contains 1 REM (Hr1) repeat.
- 翻译后修饰Phosphorylated upon DNA damage, probably by ATM or ATR.
- 细胞定位Cytoplasm. Cell membrane. Cytoplasmic, and associated with actin microfilaments and the plasma membrane.
Information by UniProt
Recombinant human ROCK2 protein 图像
Recombinant human ROCK2 protein (ab125828)参考文献
has not yet been referenced specifically in any publications.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"