概述

  • 产品名称Recombinant人RND1 protein
  • 蛋白长度Full length protein

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionQ92730
    • 种属Human
    • 序列MGSSHHHHHH SSGLVPRGSH SPYYDNVRPL CYSDSDAVLL CFDISRPETV DSALKKWRTE ILDYCPSTRV LLIGCKTDLR TDLSTLMELS HQKQAPISYE QGCAIAKQLG MKERRAPQPV VARCKLVLVG DVQCGKTAML QVLAKDCYPE TYVPTVFENY TACLETEEQR VELSLWDTSG AEIYLEGSAF TSEKSIHSIF RTASMLCLNK PSPLPQKSPV
    • 分子量25 kDa
    • 氨基酸1 to 200
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab109840 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 95 % SDS-PAGE.
    No detergents such as urea, Triton or Tween were used to purify the proteins. Purified by using anion exchange chromatography (DEAE sepharose resin) and gel filtration chromatography (Sephacryl S 200) with 20mM Tris pH 7.5, 2mM EDTA.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C or -80°C. Avoid freeze / thaw cycle.

    pH: 8.00
    Constituents: 0.32% Tris HCl, 30% Glycerol, 0.58% Sodium chloride, 0.02% DTT

常规信息

  • 别名
    • ARHS
    • FLJ42294
    • GTP binding protein RHO6
    • Ras homolog gene family member S
    • RHO 6
    • Rho family GTPase 1
    • Rho related GTP binding protein Rho6
    • RHO S
    • Rho-related GTP-binding protein Rho6
    • RHO6
    • RHOS
    • RND 1
    • Rnd1
    • RND1_HUMAN
    see all
  • 功能Lacks intrinsic GTPase activity. Has a low affinity for GDP, and constitutively binds GTP. Controls rearrangements of the actin cytoskeleton. Induces the Rac-dependent neuritic process formation in part by disruption of the cortical actin filaments. Causes the formation of many neuritic processes from the cell body with disruption of the cortical actin filaments.
  • 组织特异性Mostly expressed in brain and liver.
  • 序列相似性Belongs to the small GTPase superfamily. Rho family.
  • 细胞定位Cell membrane. Cytoplasm > cytoskeleton.
  • Information by UniProt

Recombinant Human RND1 protein 图像

  • SDS-PAGE analysis of ab109840: (1) MW marker, (2) ab109840 at 3µg
    Gel concentration: 15%

Recombinant Human RND1 protein (ab109840)参考文献

This product has been referenced in:
  • Nobes CD  et al. A new member of the Rho family, Rnd1, promotes disassembly of actin filament structures and loss of cell adhesion. J Cell Biol 141:187-97 (1998). Read more (PubMed: 9531558) »

See 1 Publication for this product

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