Recombinant人RNA Polymerase II p14.5 protein (ab81884)

概述

描述

  • 性质
    Recombinant
  • 来源
    Escherichia coli
  • 氨基酸序列
    • 种属
      Human

技术指标

Our Abpromise guarantee covers the use of ab81884 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

  • 纯度
    > 95 % SDS-PAGE.

  • 形式
    Liquid
  • 补充说明
    1 unit equals 1 nanogram of purified protein.
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped on dry ice. Upon delivery aliquot and store at -80ºC. Avoid freeze / thaw cycles.

    Preservative: None
    Constituents: 20% Glycerol, 20mM Tris HCl, 100mM Potassium chloride, 1mM DTT, 0.2mM EDTA, pH 8.0

常规信息

  • 别名
    • DNA directed RNA polymerase II 14.5 kDa polypeptide
    • DNA directed RNA polymerase II polypeptide I
    • DNA directed RNA polymerase II subunit I
    • DNA directed RNA polymerase II subunit RPB9
    • DNA-directed RNA polymerase II subunit I
    • DNA-directed RNA polymerase II subunit RPB9
    • hRPB14.5
    • POLR2I
    • Polymerase (RNA) II (DNA directed) polypeptide I 14.5kDa
    • RNA polymerase II 14.5 kDa subunit
    • RNA polymerase II subunit B9
    • RPB14.5
    • RPB9
    • RPB9_HUMAN
    see all
  • 功能
    DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template.
  • 序列相似性
    Belongs to the archaeal rpoM/eukaryotic RPA12/RPB9/RPC11 RNA polymerase family.
    Contains 1 TFIIS-type zinc finger.
  • 翻译后修饰
    Phosphorylated upon DNA damage, probably by ATM or ATR.
  • 细胞定位
    Nucleus.
  • Information by UniProt

文献

ab81884 has not yet been referenced specifically in any publications.

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