Recombinant人RGS19 protein (ab101949)

概述

描述

  • 性质Recombinant
  • 来源Escherichia coli
  • 氨基酸序列
    • AccessionP49795
    • 种属Human
    • 序列MGSSHHHHHHSSGLVPRGSHMPTPHEAEKQITGPEEADRPPSMSSHDTAS PAAPSRNPCCLCWCCCCSCSWNQERRRAWQASRESKLQPLPSCEVCATPS PEEVQSWAQSFDKLMHSPAGRSVFRAFLRTEYSEENMLFWLACEELKAEA NQHVVDEKARLIYEDYVSILSPKEVSLDSRVREGINKKMQEPSAHTFDDA QLQIYTLMHRDSYPRFLSSPTYRALLLQGPSQSSSEA
    • 分子量27 kDa including tags
    • 氨基酸1 to 217
    • 标签His tag N-Terminus

技术指标

Our Abpromise guarantee covers the use of ab101949 in the following tested applications.

The application notes include recommended starting dilutions; optimal dilutions/concentrations should be determined by the end user.

  • 应用

    SDS-PAGE

    Mass Spectrometry

  • 质谱法
    MALDI-TOF
  • 纯度> 90 % SDS-PAGE.
    ab101949 is purified using conventional chromatography techniques.
  • 形式Liquid
  • Concentration information loading...

制备和贮存

  • 稳定性和存储

    Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

    Preservative: None
    Constituents: 10% Glycerol, PBS, pH 7.4

常规信息

  • 别名
    • G alpha interacting protein
    • G protein signalling regulator 19
    • G protein, alpha-interacting protein
    • G-alpha-interacting protein
    • GAIP
    • GNAI3IP
    • Guanine nucleotide binding protein alpha inhibiting activity polypeptide 3 interacting protein
    • Regulator of G protein signalling 19
    • Regulator of G-protein signaling 19
    • RGS19
    • RGS19_HUMAN
    • RGSGAIP
    see all
  • 功能Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
  • 组织特异性Highest expression in lung. Placenta, liver and heart also express high levels of GAIP.
  • 序列相似性Contains 1 RGS domain.
  • 翻译后修饰Fatty acylated. Heavily palmitoylated in the cysteine string motif.
    Phosphorylated, mainly on serine residues.
  • 细胞定位Membrane.
  • Information by UniProt

Recombinant Human RGS19 protein 图像

  • 15% SDS-PAGE analysis of 3µg ab101949.

Recombinant Human RGS19 protein (ab101949)参考文献

ab101949 has not yet been referenced specifically in any publications.

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